| 2010-2014年临沂市手足口病病例EV71和CoxAl6病毒株流行病学特征比较 |
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| 引用本文： | 高坤. 2010-2014年临沂市手足口病病例EV71和CoxAl6病毒株流行病学特征比较[J]. 现代预防医学, 2015, 0(19): 3468-3470 |
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| 作者姓名： | 高坤 |
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| 作者单位： | 沂水县疾病预防控制中心防疫科，山东 临沂 276400 |
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| 摘 要： | 摘要:目的 比较2010-2014年临沂市手足口病实验室诊断病例中病原体为EV71和CoxAl6病毒株病例的流行病学特征。方法 从国家传染病报告信息管理系统获取2010-2014年临沂市手足口病资料，以此范围中实验室检验病原体结果为EV71和CoxAl6两种病毒株的病例为研究对象，对性别、年龄、职业、发病时间等分别进行分析比较。结果 （1）2010-2014年临沂市共报告手足口病实验室诊断病例2249例，其中病毒株为EV71的1013例，为CoxAl6的874例，分别占45.04%和38.86%。（2）病毒株为EV71和CoxAl6的病例的男女比例分别为2∶1和1.95∶1；年龄分布均以0～3岁为主，分别占87.59％和83.41％；职业分布以散居儿童为主，分别占92.08%和87.30%；发病时间方面，CoxAl6发病高峰期出现在4-7月，而EV71除3-7月出现的第一个发病高峰外，在10-11月份又出现了第二个小高峰；在重症病例病毒阳性率上，EV71和CoxAl6分别占66.95%和27.12%。结论 2010-2014年临沂市手足口病的发病率居高不下，主要病原体依然为EV71和CoxAl6，二者在性别、年龄、职业分布方面无明显差异，但在发病时间分布上却有所不同，CoxAl6呈明显的单峰分布，而EV71则出现两个发病高峰，另外EV71仍是重症病例的主要致病病毒。
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| 关 键 词： | 关键词:手足口病 流行特征 EV71 CoxAl6 |
Epidemiological analysis on hand-foot-mouth disease of EV71 and CoxAl6 virus in Linyi, 2010-2014 |
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| GAO Kun. Epidemiological analysis on hand-foot-mouth disease of EV71 and CoxAl6 virus in Linyi, 2010-2014[J]. Modern Preventive Medicine, 2015, 0(19): 3468-3470 |
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| Authors: | GAO Kun |
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| Affiliation: | Department of Epidemic Prevention, Centre of Epidemic Prevention, Yishui, Linyi, Shandong 276400, China |
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| Abstract: | Abstract: Objective To compare epidemiological characteristics of diagnosed cases of EV71 and CoxA16 in Linyi hand-foot- mouth laboratory from 2010 to 2014. Methods We got HFMD infectious disease reporting information in Linyi from 2010 to 2014 from the national information management system. The gender, age, occupation, onset time were analyzed and compared. Results From 2010 to 2014, Linyi reported 2249 HFMD cases of laboratory diagnosis of cases, including 1013 cases of EV71 and 874 cases of CoxAl6 virus strains, accounting for 45.04% and 38.86%. The proportions of men and women for EV71 and CoxAl6 virus strains were 2: 1 and 1.95: 1. The age distribution are 0-3 years old, accounting for 87.59% and 83.41%, respectively. The age mainly distributed as 0-3 years old, accounting for 87.59% and 83.41%, respectively. Occupational distribution of scattered children, accounting for 92.08% and 87.30%, respectively. Time of onset, CoxAl6 morbidity peak appeared in April to July months. But EV71 except March to July appeared outside the first peaks. There was a second small peak in November. The virus-positive rate in severe cases, and EV71 and CoxAl6 accounted for 66.95% and 27.12%, respectively. Conclusion The incidence of HFMD remains high in Linyi from 2010 to 2014. The main remaining pathogens are EV71 and CoxAl6. No significant difference between the two in terms of gender, age, occupation distribution, but the time of onset is different. CoxAl6 showed a unimodal distribution, while there are two peaks for EV71. EV71 is still the major pathogenic viruses in severe cases. |
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| Keywords: | Keywords: Hand-foot-mouth disease Epidemiological characteristics CoxsackievirusAl6 Enterovirus 71 |
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