Genetics of Human-Mouse Somatic Cell Hybrids: Linkage of Human Genes for Lactate Dehydrogenase-A and Esterase-A4 |
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Authors: | Thomas B. Shows |
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Affiliation: | 1.Roswell Park Memorial Institute, New York State Department of Health, N.Y. 14203 |
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Abstract: | By use of human-mouse somatic cell hybrids, an autosomal gene linkage has been determined for the human loci controlling the phenotypes of lactate dehydrogenase-A (EC 1.1.1.27) and esterase-A(4) (EC 3.1.1.2). These structural loci were not linked to the lactate dehydrogenase-B, peptidase-B linkage, the X chromosome, the E(17) chromosome, or to nine other enzyme phenotypes examined. |
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