| NICU早产儿PICC导管相关血流感染高危因素的Meta分析 |
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| 引用本文： | 段小凤1,王松2,李胜玲1. NICU早产儿PICC导管相关血流感染高危因素的Meta分析[J]. 现代预防医学, 2020, 0(9): 1708-1713 |
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| 作者姓名： | 段小凤1 王松2 李胜玲1 |
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| 作者单位： | 1.宁夏医科大学护理学院，银川 750004；2.四川大学华西护理学院，四川 成都 610041 |
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| 摘 要： | 目的 通过Meta分析客观地确定NICU早产儿PICC导管相关血流感染的主要高危因素，为预防早产儿PICC导管相关血流感染提供一定的循证证据支持。方法 在线检索CNKI、万方、维普、Cochrane Library、PubMed、EMBASE等数据库，检索年限从各数据库建库起始至2019年1月，有关公开发表的早产儿PICC导管相关血流感染高危因素的文献，由两名研究员独立完成文献筛选、质量评价及资料提取，采用RevMan5.3软件进行Meta分析。结果 经筛选共纳入10篇文献（中文1篇，英文9篇）进行Meta分析。胎龄＜32周(OR=0.26, 95%CI:0.10~0.66)，出生体重＜750g(OR=0.53, 95%CI:0.41~0.69)，股三角部位置管(OR=1.67, 95%CI:1.31~2.11)，置管耗时≥60min(OR=0.61, 95%CI:0.38~0.97)，留置管时间≥30天(OR=2.41, 95%CI:1.75~3.31)，留置CVC导管数量≥2个(OR=0.21, 95%CI:0.17~0.25)是高危因素。结论 胎龄愈小、出生体重越低、经股三角部位置管、置管耗时和导管留置时间越长、留置多个CVC导管是早产儿PICC置管后发生导管相关血流感染的高危因素，医护人员可采取有效预防措施，降低导管相关血流感染的发生率。
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| 关 键 词： | 早产儿 PICC 导管相关血流感染 危险因素 Meta分析 |
High risk factors for PICC catheter-related bloodstream infection in preterm infants in NICU: a meta-analysis |
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| DUAN Xiao-feng,WANG Song,LI Sheng-ling. High risk factors for PICC catheter-related bloodstream infection in preterm infants in NICU: a meta-analysis[J]. Modern Preventive Medicine, 2020, 0(9): 1708-1713 |
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| Authors: | DUAN Xiao-feng WANG Song LI Sheng-ling |
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| Affiliation: | *Nursing College, Ningxia Medical University, Yinchuan, Ningxia 750004, China |
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| Abstract: | Objective To investigate the main risk factors of PICC catheter-related bloodstream infection in premature infants in NICU by meta-analysis, and to provide a theoretical basis for the prevention of PICC catheter-related bloodstream infection in premature infants. Methods CNKI, Wanfang, Weipu, Cochrane Library, PubMed and EMBASE databases were retrieved online. Literatures on high risk factors of PICC catheter-related blood flow infections in premature infants published from date of the establishment of databases to January 2019 were independently screened, evaluated and extracted by two researchers. RevMan 5.3 software was used for meta-analysis. Results A total of 10 literatures (1 in Chinese and 9 in English) were selected for meta-analysis. The gestational age<32 weeks (OR=0.26, 95%CI: 0.10-0.66), birth weight<750 g (OR=0.53, 95%CI: 0.41-0.69), catheterization at triangle of femur (OR=1.67, 95%CI: 1.31-2.11), catheterization time ≥60 minutes (OR=0.61, 95%CI: 0.38-0.97), indwelling catheter time≥30 days (OR=2.41, 95%CI: 1.75-3.31), and the number of indwelling CVC catheters≥2 (OR=0.21, 95%CI: 0.17-0.25) were high risk factors. Conclusion The smaller the gestational age, the lower the birth weight, the position of the transfemoral triangle, the longer time spent in the catheterization process and the catheter indwelling time, and the retention of multiple CVC catheters are the main causes of catheter-related bloodstream infection after PICC placement in preterm infants. Medical staff can take effective preventive measures against these high-risk factors to reduce the incidence of catheter-related bloodstream infections. |
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| Keywords: | Premature infants PICC Catheter-related bloodstream infections Risk factors Meta-analysis |
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