|
|||||
|
|
| 载药中空微球研究进展 | |
| 引用本文： | 韩国华,李美琴,朱澄云. 载药中空微球研究进展[J]. 沈阳药科大学学报, 2011, 28(7): 575-580 |
| 作者姓名： | 韩国华 李美琴 朱澄云 |
| 作者单位： | （1. 沈阳药科大学 药学院，辽宁 沈阳 110016；2. 浙江医药股份有限公司新昌制药厂，浙江 绍兴 312500） |
| 摘 要： | 目的介绍载药中空微球的研究进展。方法对中空微球的制备方法以及体内外漂浮性能的评价方法进行综述。结果该剂型可以延长药物在胃内的滞留时间,提高生物利用度并减少给药次数。结论中空微球是具有开发潜力的漂浮系统,具有广阔的发展前景。 |
| 关 键 词： | 中空微球 漂浮 多单元 给药系统 |
| 收稿时间： | 2010-07-19 |
Research progress of drug-loaded hollow microspheres |
|
| HAN Guo-hua,LI Mei-qin,ZHU Cheng-yun. Research progress of drug-loaded hollow microspheres[J]. Journal of Shenyang Pharmaceutical University, 2011, 28(7): 575-580 | |
| Authors: | HAN Guo-hua LI Mei-qin ZHU Cheng-yun |
| Affiliation: | 1(1.School of Pharmacy,Shenyang Pharmaceutical University,Shenyang 110016,China;2.Zhejiang Medicine Co.Ltd.,Xinchang Pharmaceutical Factory,Shaoxing 312500,China) |
| Abstract: | Objective To review the research progress of drug-loaded hollow microspheres. Methods The preparation and floating characterization in vivo and in vitro of the hollow microspheres were introduced on the basis of related references. Results Hollow microspheres have the advantage of prolonging the gastric retention time, enhancing the bioavailability and decreasing dosing frequency. Conclusion Hollow microspheres are considered to be gastric floating drug delivery system with great development potential. |
| Keywords: | hollow microsphere floating multiple-unit drug delivery system |
| 本文献已被 CNKI 等数据库收录！ | |
| 点击此处可从《沈阳药科大学学报》浏览原始摘要信息 | |
| 点击此处可从《沈阳药科大学学报》下载全文 | |