| 日照市2002年不同人群乙肝抗体水平监测流行病学分析 |
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| 引用本文： | 郑祺,韩敬建,王茂慈. 日照市2002年不同人群乙肝抗体水平监测流行病学分析[J]. 疾病监测, 2004, 19(4): 125-127. DOI: 10.3784/j.issn.1003-9961.2004.4.125 |
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| 作者姓名： | 郑祺 韩敬建 王茂慈 |
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| 作者单位： | 山东省日照市卫生防疫站,山东,日照,276800;日照市东港区人民医院 |
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| 摘 要： | 目的 为了观察日照市不同地区人群HBV标志物的变化趋势。方法 采用单纯随机抽样的方法对该市东港区405名不同年龄人群进行了调查,采静脉血2 ml,用ELA法检测HBsAg和抗-HBs。结果 HB-sAg平均携带率为2.96％,20-40岁组最高为5.46％,其他各年龄组之间无显著差异。抗-HBs平均阳性率为60.99％,<2岁最高为81.54％,8岁组最低为41.67％,二者之间有显著统计学意义,但HBsAg携带率无差异,有乙肝疫苗免疫史抗-HBs阳性率为62.50％,无免疫史者抗-HBs阳性率为36.07％。结论 接种乙肝疫苗是预防乙型肝炎最有效的措施,但接种乙肝4年后抗-HBs阳性率迅速下降,通过加强免疫抗-HBs可迅速提高。如果从提高抗-HBs阳性率的角度考虑,在新生儿全程接种乙肝疫苗5年后,对抗-HBs阴性者有必要进行加强免疫。在免疫后的10年内无需普遍实施加强免疫。
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| 关 键 词： | 乙型肝炎 监测 流行病学 免疫接种 |
| 文章编号： | 1003-9961(2004)04-0125-02 |
| 收稿时间： | 2004-02-15 |
| 修稿时间： | 2004-02-15 |
Analysis on Epidemiological Surveillance of HBV Antibody of Different Crowd in Rizhao City 2002 |
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| ZHENG Qi,et al Sanitation and Anti-epidemic Station of Rizhao City of Shandong Province,Shandong Rizhao. Analysis on Epidemiological Surveillance of HBV Antibody of Different Crowd in Rizhao City 2002[J]. Disease Surveillance, 2004, 19(4): 125-127. DOI: 10.3784/j.issn.1003-9961.2004.4.125 |
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| Authors: | ZHENG Qi et al Sanitation Anti-epidemic Station of Rizhao City of Shandong Province Shandong Rizhao |
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| Affiliation: | 1.Sanitation and Anti-epidemic Station of Rizhao City of Shandong Province;Shandong Rizhao 276800; |
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| Abstract: | Objective To explore the HBV mark’s changing tendence in Rizhao City.Method To adopt the simple random sampling method to investigate 405 persons of different age in Donggang district; and to collect 2 ml of vein blood to examine HBsAg and anti-HBs with ELA method.Results The average rate of HBsAg carrying was 2.96%,and the highest rate of HBsAg crrying was in the group of 20-40 years old(5.46%).There were no significant different among other groups.Meanwhile,the average positive rate of anti-HBs was 60.99%,the highest positive rate was in the group of <2 years old (81.54%),and the lowest positive rate was in the group of 8 years old. There was a statistical significant different between them. In people who had HBV vaccine immunity experience,the positive rate of anti- HBs was 62.50%,and in those who hadn't HBV vaccine immunity experience was 36.07%,Conclusions The inoculability of HBV vaccine was proved to be efficacious against HBV,but positive rate of anti-HBs declined rapidly after 4 years of HBV vaccine inoculability. In order to improve the positive rate of anti-Hbe, it was necessary to augment immunity to neonates who were negative of anti-HBs after 5 years of the whole course of HBV vaccine in-ocubalityl Otherwise,it wasn't neccssary to apply augmenting immunity after 10 years. |
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| Keywords: | HBV Examine Epidemiology Immunity inoculability |
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