| T1bSM2期食管鳞状细胞癌内镜治疗的安全性和有效性分析 |
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| 引用本文： | 吕昆明,袁静,柴宁莉,冯秀雪,卢忠生,张文刚,汤小伟,陈倩倩,令狐恩强. T1bSM2期食管鳞状细胞癌内镜治疗的安全性和有效性分析[J]. 中华腔镜外科杂志(电子版), 2020, 13(3): 173-176. DOI: 10.3877/cma.j.issn.1674-6899.2020.03.010 |
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| 作者姓名： | 吕昆明 袁静 柴宁莉 冯秀雪 卢忠生 张文刚 汤小伟 陈倩倩 令狐恩强 |
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| 作者单位： | 1. 100853 北京，解放军医学院；100853 北京，解放军总医院第二医学中心消化内科2. 100853 北京，解放军总医院第一医学中心病理科3. 100853 北京，解放军总医院第一医学中心消化内科 |
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| 基金项目： | 国家重点研发计划(2016YFC1303601) |
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| 摘 要： | 目的回顾性分析内镜切除术治疗T1bSM2期(黏膜下层≥200 μm)早期食管鳞状细胞癌的安全性、有效性。 方法选取2009年1月至2017年7月于解放军总医院第一医学中心接受内镜切除术治疗且术后病理提示病变累及M3层(黏膜肌层)、SM1层(黏膜下层<200 μm)和SM2层(黏膜下层≥200 μm)的79例患者为研究对象，根据浸润深度分为相对适应证组和拓展适应证组，分析比较两组患者的基本资料及术后并发症的差异，Kaplan-Meier生存分析总体生存率及无进展生存率。 结果两组患者的基本资料、术后并发症、预后、总体生存率及无进展生存率比较，差异无统计学意义。 结论对于T1bSM2期食管鳞状细胞癌，内镜切除术也是一种可以选择的治疗方式。
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| 关 键 词： | 内镜切除术 内镜黏膜剥离术 早期食管鳞状细胞癌 拓展适应证 |
| 收稿时间： | 2020-04-19 |
The safety and efficacy of endoscopic treatment of T1bSM2 esophageal squamous cell carcinoma |
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| Kunming Lyu,Jing Yuan,Ningli Chai,Xiuxue Feng,Zhongsheng Lu,Wengang Zhang,Xiaowei Tang,Qianqian Chen,Enqiang Linghu. The safety and efficacy of endoscopic treatment of T1bSM2 esophageal squamous cell carcinoma[J]. Chinese Journal of Laparoscopic Surgery ( Electronic Editon), 2020, 13(3): 173-176. DOI: 10.3877/cma.j.issn.1674-6899.2020.03.010 |
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| Authors: | Kunming Lyu Jing Yuan Ningli Chai Xiuxue Feng Zhongsheng Lu Wengang Zhang Xiaowei Tang Qianqian Chen Enqiang Linghu |
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| Affiliation: | 1. Chinese PLA Medical School, Beijing 100853, China; Department of Gastroenterology, Second Medical Center of Chinese PLA General Hospital, Beijing 100853, China2. Department of Pathology, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China3. Department of Gastroenterology, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China |
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| Abstract: | ObjectiveTo analysis of the safety and efficacy of endoscopic resection in the treatment of early esophageal squamous cell carcinoma of stage T1bSM2 (submucosa ≥200 μm). MethodsThe clinical data of 79 patients undergoing endoscopic resection surgery and postoperative pathology showed that the lesions involved the M3 layer (mucosal muscle layer) , SM1 layer (submucosal layer <200 μm) and SM2 layer (submucosal layer ≥200 μm)was retrospectively analyzed.According to the depth of infiltration, the patients was divided into two groups including relative indication group and expanded the indication group , The basic data and postoperative complications of the two groups were analyzed and compared between the two groups.Kaplan-Meier survival analysis was employed to analyze the overall survival rate and progression-free survival rate. ResultsThere was no significant difference in basic data, postoperative complications, prognosis, overall survival rate and progression-free survival rate between the two groups. ConclusionsEndoscopic treatment can be used as a optional method in patients with T1bSM2 stage esophageal squamous cell carcinoma. |
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| Keywords: | Endoscopic resection Endoscopic submucosal dissection Early esophageal squamous cell carcinoma Expanded the indication |
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