| 慢性肾功能不全患者iPTH与LVH及收缩功能的临床分析 |
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| 引用本文： | 林鑫,程世平,查艳. 慢性肾功能不全患者iPTH与LVH及收缩功能的临床分析[J]. 广东医学, 2011, 32(12) |
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| 作者姓名： | 林鑫 程世平 查艳 |
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| 作者单位： | 贵州省人民医院 |
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| 摘 要： | 目的： 心血管并发症是慢性肾功能不全患者一个常见而严重并发症。患者常伴继发性甲状旁腺功能亢进和甲状旁腺激素（iPTH）的增高,为了解iPTH的增高与左心室肥厚与收缩功能的关系特作此研究。 方法： 通过对258例慢性肾功能不全患者心脏超声与心功能检测及与血iPTH的相关分析, 了解慢性肾功能不全患者iPTH与LVH及收缩功能。 结果：1.随肾功能不全Ccr的下降,iPTH水平渐升高,EF下降,LVMI值加大,心脏损害加重。2. CKD3-5期iPTH与EF负相关,与LVMI正相关（P＜0.05）3.不同原发疾病致肾功能不全iPTH的表达无显著差异,但高血压肾动脉硬化,糖尿病肾病组所致心脏损害较慢性肾小球肾炎及其它病因组有统计学差异（P＜0.05）。结论： iPTH增高是引起LVH与左心收缩功能改变的重要因素之一。
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| 关 键 词： | 左心室肥厚 慢性肾功能不全 甲状旁腺激素 甲状旁腺功能亢进 |
Increased serum parathyroid hormone level is associated with left ventricular hypertrophy and systolic dysfunction in chronic renal failure |
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| LIN Xin,CHENG Shi-ping,ZHA Yan. Increased serum parathyroid hormone level is associated with left ventricular hypertrophy and systolic dysfunction in chronic renal failure[J]. Guangdong Medical Journal, 2011, 32(12) |
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| Authors: | LIN Xin CHENG Shi-ping ZHA Yan |
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| Abstract: | Objective To study the association between the increased iPTH and left ventricular hypertrophy(LVH) or left ventricular systolic dysfunction in patients with renal failure. Methods Echocardiography was performed and serum iPTH was determined in 258 patients with chronic renal failure.The correlation between serum iPTH and LVH or systolic dysfunction was analyzed. Results(1)With the decline of creatinine clearance,increased iPTH and LVMI,with lower EF were observed.(2)Significantly negative correlation was r... |
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| Keywords: | chronic renal failure parathyroid hormone hyperparathyroidism left ventricular hypertrophy |
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