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LGI1抗体相关边缘叶脑炎1例及文献复习
引用本文:孙美,侯晓夏,金善泉,沈飞飞,程虹. LGI1抗体相关边缘叶脑炎1例及文献复习[J]. 临床荟萃, 2019, 34(3): 273. DOI: 10.3969/j.issn.1004-583X.2019.03.015
作者姓名:孙美  侯晓夏  金善泉  沈飞飞  程虹
作者单位:1.南京医科大学第一附属医院 神经内科,江苏 南京 210029;2.苏州市立医院 神经内科,江苏 苏州 215000
基金项目:江苏省人社厅“六大人才高峰”第12批高层次人才资助项目----急性脑梗死早期外周血中的动态变化及预后评估中作用的研究(WSN-025)
摘    要:LGI1抗体相关的边缘叶脑炎是以突发认知及情感变化、癫痫发作为主要特点的自身免疫性疾病,很少伴发肿瘤且对免疫治疗反应较好,及时诊断及治疗有助于患者的远期预后。报道本院收治的LGI1抗体脑炎1例。

关 键 词:脑炎  抗体  认知障碍  免疫治疗  

LGI1 antibody related limbic encephalitis: a case report and literature review
Sun Mei,Hou Xiaoxia,Jin Shanquan,Shen Feifei,Cheng Hong. LGI1 antibody related limbic encephalitis: a case report and literature review[J]. Clinical Focus, 2019, 34(3): 273. DOI: 10.3969/j.issn.1004-583X.2019.03.015
Authors:Sun Mei  Hou Xiaoxia  Jin Shanquan  Shen Feifei  Cheng Hong
Affiliation:1. Department of Neurology, the First Affiliated Hospital of Nanjing Medical University, ;Nanjing  210029, China;  2. Department of Neurology, Suzhou Municipal Hospital, Suzhou 215000, China
Abstract:LGI1 antibody related limbic encephalitis is an autoimmune disease characterized by sudden cognitive, and emotional changes and epileptic seizures. It rarely coincides with tumor and has a better response to immunotherapy. The early diagnosis and appropriate treatment suggest a better prognosis for patients. A case of LGI1 antibody related limbic encephalitis admitted to our hospital is reported.
Keywords:encephalitis,antibody  cognitive impairment,immunotherapy,
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