| 干细胞治疗人体寄生虫病研究进展 |
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| 引用本文： | 黎文华,王鹏. 干细胞治疗人体寄生虫病研究进展[J]. 中国血吸虫病防治杂志, 2016, 28(6): 740-744 |
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| 作者姓名： | 黎文华 王鹏 |
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| 作者单位： | 1 江苏省无锡市第二人民医院、南京医科大学附属无锡第二医院消化内科（无锡 214002）；2 江苏省无锡市第二人民医院、南京医科大学附属无锡第二医院神经外科 |
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| 基金项目： | 江苏省血地寄防应用性科研项目（X201117） |
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| 摘 要： | 干细胞是一类具有自我复制、自我更新和多向分化潜能的原始细胞，其在一定条件下可分化为多种功能细胞，生成人体各种组织器官。干细胞疗法是通过将新的干细胞引入到受损组织，促进因创伤、疾病、老化而受损的人体组织再生，从而修复或替换受损组织，以达到治疗疾病的目的。既往研究证实，干细胞疗法可用于癌症、糖尿病、神经系统疾病、自身免疫性疾病、心血管疾病、血液病等多种人类疾病治疗，显示了其广泛的临床应用前景。本文主要就干细胞疗法治疗人体寄生虫感染作一综述。
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| 关 键 词： | 干细胞；干细胞疗法；寄生虫病；血吸虫病；疟疾；利什曼病；美洲锥虫病 |
Advances in research of stem cell therapy for human parasitic diseases: a review |
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| LI Wen-Hua,WANG Peng. Advances in research of stem cell therapy for human parasitic diseases: a review[J]. Chinese journal of schistosomiasis control, 2016, 28(6): 740-744 |
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| Authors: | LI Wen-Hua WANG Peng |
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| Affiliation: | 1 Department of Gastroenterology| Wuxi No. 2 Hospital Affiliated to Nanjing Medical University| Wuxi 214002| China； 2 Department of Neurosurgery| Wuxi No. 2 Hospital Affiliated to Nanjing Medical University| China |
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| Abstract: | The stem cell is a class of primitive cells with self?renewal， and multiple pluripotent potential capacities， which can differentiate into multiple specialized cells and generate human organs and tissues. Stem cell therapy is an interventional treatment that introduces new stem cells to damaged tissues， which facilitates the regeneration of trauma， disease and ageing?induced damaged human tissues to repair or replace the damaged tissues， thereby achieving the goal of disease treatment. It has been proved that the stem cell therapy is effective in the treatment of multiple human diseases， including cancer， diabetes， neurological disorders， autoimmune diseases， cardiovascular disorders and blood diseases. This review summarizes the advances in the research of stem cell therapy for human parasitic infections. |
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| Keywords: | Stem cell； Stem cell therapy； Parasitic disease； Schistosomiasis； Malaria； Leishmaniasis； Chagas disease |
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