| 骨诱导活性材料在修复牙槽突裂中的临床研究 |
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| 引用本文： | 佘小明,张倩,田锟,杨丽,熊贵发. 骨诱导活性材料在修复牙槽突裂中的临床研究[J]. 华西口腔医学杂志, 2010, 28(4): 391-394. DOI: 10.3969/j.issn.100-1182.2010.04.013 |
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| 作者姓名： | 佘小明 张倩 田锟 杨丽 熊贵发 |
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| 作者单位： | 贵阳市口腔医院颌面外科,贵州贵阳,550002;淄博市第-人民医院口腔科,山东淄博,255200 |
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| 摘 要： | 目的研究骨诱导活性材料（OAM）修复牙槽突裂骨缺损的可行性和可靠性。方法将27例年龄9～20岁的单侧牙槽突裂患者分为试验组和对照组,试验组（12例）采用OAM进行牙槽突裂修复,对照组（15例）采用自体髂骨质松质进行牙槽突裂移植修复。术后6个月,采用CT扫描及三维重建方法观察牙槽突裂重建情况,比较2种材料修复牙槽突裂骨缺损的效果。结果术后6个月,2组患者各有2例植骨失败,其余患者牙槽突连续性均得到恢复,未萌尖牙向植骨区移动并萌出。2组患者植骨成功率之间的差异无统计学意义（P＝1.000）。结论OAM修复牙槽突裂有明显的成骨作用且不阻碍尖牙的正常萌出,其成骨效果与自体髂骨骨松质修复效果相似。
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| 关 键 词： | 骨诱导活性材料 牙槽突裂 骨缺损 植骨 |
| 收稿时间： | 2010-08-25 |
| 修稿时间： | 2010-08-25 |
Clinical research on repairing alveolar cleft with osteoinduction active material |
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| SHE Xiao-ming,ZHANG Qian,TIAN Kun,YANG Li,XIONG Gui-fa. Clinical research on repairing alveolar cleft with osteoinduction active material[J]. West China journal of stomatology, 2010, 28(4): 391-394. DOI: 10.3969/j.issn.100-1182.2010.04.013 |
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| Authors: | SHE Xiao-ming ZHANG Qian TIAN Kun YANG Li XIONG Gui-fa |
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| Affiliation: | 1. Dept. of Oral and Maxillofacial Surgery, Guiyang Stomatological Hospital, Guiyang 550002, China; 2. Dept. of Stomatology, The First People′ s Hospital of Zibo, Zibo 255200, China |
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| Abstract: | Objective To study the feasibility and authenticity of repairing alveolar defects in alveolar cleft patients with osteoinduction active material（OAM） in clinic. Methods Twenty-seven cases of alveolar defect chosen from clinic were divided into two groups（test group and control group）. For test group（12 cases）, OAM was transplanted to repair the alveolar cleft. For control group（15 cases）, autogenous ilium cancellous bone were transplanted into the defect region to repair alveolar cleft. At 6 months after operation, CT and three-dimensional reconstruction were used to observe alveolar appearance, and the effect and clinical success rate of recover alveolar cleft by using different repair material were compared. Results In the 27 cases, all the maxillary continuity was restored except two of test group and two of control group. There was no significant difference between test group and control group regarding the clinical success rate of the alveolar cleft repair（P=1.000）. Conclusion OAM was used to repair the alveolar cleft that can result in new bone formations and the burgeon of canines from the bone grafted areas. There is no significant difference between OAM and autogenous ilium cancellous bone regarding the effect of the alveolar cleft repair. |
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| Keywords: | osteoinduction active material alveolar cleft bone defect bone graft |
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