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| 右美托咪定与丙泊酚用于无痛拔牙术清醒镇静的临床观察 | |
| 引用本文： | 顾红政,冯英,汤建高. 右美托咪定与丙泊酚用于无痛拔牙术清醒镇静的临床观察[J]. 口腔医学, 2010, 30(12): 727-728,746 |
| 作者姓名： | 顾红政 冯英 汤建高 |
| 作者单位： | [1]江苏大学附属四院口腔科,镇江212001 [2]江苏大学附属四院麻醉科,镇江212001 |
| 摘 要： | 目的 观察右美托咪定与丙泊酚用于无痛拔牙术时清醒镇静的效果和手术安全性。方法 90例门诊拔牙患者随机分成3组,Ⅰ组(右美托咪定),Ⅱ组(丙泊酚),Ⅲ组(对照)。记录Ⅰ、Ⅱ两组患者入睡时间、自然清醒时间,术中药物追加次数、镇静评分及术后恶心、呕吐的发生率,监测3组患者脉搏血氧饱和度(Pulse oxygen saturation,SpO2)、平均动脉压(Mean arterial pressure,MAP)、心率(heartrate,HR)、呼吸频率(Respiratory rate,RR)生命体征。结果 患者入睡时间、自然清醒时间Ⅱ组短于Ⅰ组(P<0.05),术中镇静评分Ⅱ组与Ⅰ组差异有统计学意义(P<0.05),两组生命体征术前、术中、术后没有明显变化(P>0.05),对照组术中MAP和HR有明显波动,与术前、术后相比差异有统计学意义(P<0.05),与观察组相比差异有统计学意义(P<0.05)。两组术后恶心、呕吐的发生率差异没有统计学意义(P>0.05)。患者满意度Ⅰ组高于Ⅱ组和对照组,差异有统计学意义(P<0.05)。结论 右美托咪定用于门诊无痛拔牙术与丙泊酚相比,清醒镇静程度满意、术中配合好,使用安全,值得临床推广运用。 |
| 关 键 词： | 右美托咪定 丙泊酚 清醒镇静 无痛拔牙 |
Clinical study of dexmedetomidine and propofol in conscious sedation and pain-free exodontias |
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| GU Hong-zheng,FENG Ying,TANG Jian-gao. Clinical study of dexmedetomidine and propofol in conscious sedation and pain-free exodontias[J]. Stomatology, 2010, 30(12): 727-728,746 | |
| Authors: | GU Hong-zheng FENG Ying TANG Jian-gao |
| Affiliation: | .(Department of Stanatology,4st Affiliated Hospital of Jiangsu University,Zhenjiang 212001,China) |
| Abstract: | Objective To observe the clinical use of dexmedetomidine and propofol in conscious sedation and pain-free exodontias.Methods Ninty outpatients of exodontia were randomly divided into three groaps： Ⅰ（dexmedetomidine） group,Ⅱ （propofol） group and Ⅲ（control） group.The time of falling asleep and regainning consciousness was recorded. SpO2、MAP、HR 、RR and depth of controlled sedafion duriny operation were recorded at the same time. Results The time of falling asleep and regainning consciousness in Ⅱ group was shorter than that in Ⅰgroup,（P0.05）.There was no clear difference between these two groups in SpO2、MAP、HR、RR.The hemodynamics kept steady,but fluctuated greatly in control group,and had no apparent statistical difference.Conclusions The effect and safety of anesthesia combined with dexmedetomidine was significantly better than with propofol. |
| Keywords: | dexmedetomidine Propofol conscious sedation pain free exodontia. |
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