| 西安市首诊HIV/AIDS患者流行病学及临床特征分析 |
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| 引用本文： | 张艳, 靳娟, 李飞宇, 康立, 李俊丽, 许荣放, 赵生魁. 西安市首诊HIV/AIDS患者流行病学及临床特征分析[J]. 中国公共卫生, 2016, 32(12): 1641-1644. DOI: 10.11847/zgggws2016-32-12-10 |
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| 作者姓名： | 张艳 靳娟 李飞宇 康立 李俊丽 许荣放 赵生魁 |
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| 作者单位： | 1.西安市第八医院艾滋病科, 陕西 西安 710061 |
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| 摘 要： | 目的 探讨接受高效抗逆转录病毒治疗（HAART）的首诊艾滋病病毒感染者和艾滋病（HIV/AIDS）患者流行病学及临床特征。方法 回顾性分析西安市传染病医院2005-2013年接受HAART首诊HIV/AIDS患者临床及实验室资料。结果 1 243例HIV/AIDS患者中，多为中青年男性，传播途径以同性传播为主。26.06%（324/1 243）的出现临床症状或体征，常见的机会性感染有发热、持续腹泻、鹅口疮、皮肤损害、耶氏肺孢子菌肺炎等。体质指数（BMI）、血红蛋白、CD4、CD8、WBC水平从I期到IV期逐渐降低，且有统计学差异（P<0.01）。CD4计数与机会性感染关系密切。结论 HIV/AIDS患者治疗中，应积极治疗各种机会性感染，密切关注CD4、CD8等实验室指标的变化情况。
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| 关 键 词： | HIV感染 艾滋病 流行病学特征 临床特征 |
| 收稿时间： | 2015-06-18 |
Epidemiological and clinical characteristics of first diagnosed HIV infected persons in Xi'an city |
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| ZHANG Yan, JIN Juan, LI Fei-yu.et al, . Epidemiological and clinical characteristics of first diagnosed HIV infected persons in Xi'an city[J]. Chinese Journal of Public Health, 2016, 32(12): 1641-1644. DOI: 10.11847/zgggws2016-32-12-10 |
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| Authors: | ZHANG Yan JIN Juan LI Fei-yu.et al |
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| Affiliation: | 1.Department of AIDS, The Eighth Hospital of Xi'an Municipality, Xi'an, Shaanxi Province 710061, China |
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| Abstract: | Objective To investigate epidemiological and clinical characteristics of first diagnosed human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) patients receiving highly active antiretroviral therapy (HAART) in Xi'an city.Methods Medical records of 1 243 HIV/AIDS patients first diagnosed and receiving HAART at Xi'an Municipal Infectious Disease Hospital from 2005 through 2013 were collected and analyzed retrospectively.Results The majority of the patients were young and middle-aged males and were infected through homosexual contact.Of all the HIV infections,324 (26.06%) showed clinical symptoms of AIDS,with signs of common opportunistic infections including fever,persistent diarrhea,thrush,skin lesion,and Pneumocystis jiroveci pneumonia; body mass index,hemoglobin,and count number of CD4,CD8 and white blood cells were significantly decreased with the severity of the AIDS (all P<0.01) and there was a close relationship between CD4 count and the incident of opportunistic infections among the AIDS patients.Conclusion Various opportunistic infections should be treated in time and close attention should be paid to the changes in CD4 and CD8 count among AIDS patients. |
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| Keywords: | human immunodeficiency virus infection acquired immunodeficiency syndrome prevalence characteristics clinical characteristics |
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