| 硝呋太尔-制霉菌素阴道栓治疗细菌性阴道病的疗效及安全性分析 |
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| 引用本文： | 刘玉峰. 硝呋太尔-制霉菌素阴道栓治疗细菌性阴道病的疗效及安全性分析[J]. 中国现代应用药学, 2011, 28(10): 962-965. |
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| 作者姓名： | 刘玉峰 |
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| 作者单位： | 1.松阳县人民医院，浙江 松阳 323400 |
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| 摘 要： | 目的 评价硝呋太尔-制霉菌素阴道栓治疗细菌性阴道病的疗效和安全性。 方法 本研究采用随机对照试验。试验组80例，对照组78例，分别给予硝呋太尔-制霉菌素栓和甲硝唑栓，疗程分别为6 d和7 d。分别于停药后3~5 d 和停药后月经来潮干净3~7 d观察疗效和安全性。 结果 停药后3~5 d，试验组和对照组有效率分别为90.0%和82.5%，差异无统计学意义(P>0.05)，两组间疗效比较无显著差异(P>0.05)；停药后月经来潮干净后3~7 d，试验组和对照组有效率分别为82.5%和73.1%，差异无统计学意义(P>0.05)，两组疗效无显著差异(P>0.05)。试验中未见严重不良反应，不良反应发生率试验组低于对照组(P<0.05)。 结论 硝呋太尔-制霉菌素栓治疗细菌性阴道病安全、有效。
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| 关 键 词： | 阴道病 细菌性 硝呋太尔-制霉菌素栓 甲硝唑栓 |
| 收稿时间： | 2010-12-27 |
Efficacy and Safety of Nifuratel-nysfungin Suppository in the Treatment of Bacterial Vaginosis |
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| LIU Yufeng. Efficacy and Safety of Nifuratel-nysfungin Suppository in the Treatment of Bacterial Vaginosis[J]. Chinese Journal of Modern Applied Pharmacy, 2011, 28(10): 962-965. |
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| Authors: | LIU Yufeng |
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| Affiliation: | 1.The People’s Hospital of Songyang, Songyang 323400, China |
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| Abstract: | OBJECTIVE To evaluate the efficacy and safety of nifuratel-nysfungin suppository in the treatment of bacterial vaginosis. METHODS A randomized and controlled clinical trial was conducted. The 80 patients in trial group were treated with nifuratel-nysfungin suppository and 78 patients in control group were given metronidazole suppository. Six successive days were taken as a course for nifuratel-nysfungin suppository group and seven successive days for metronidazole suppository. The efficacy and safety were observed respectively 3-5 d after treatment and 3-7 d after menorrhea. RESULTS The efficacy rate was 90.0% in trial group and 82.5% in control group on 3-5 d after treatment (P>0.05). There was no significant difference in clinical efficacy between two groups(P>0.05). The efficacy rate was 82.5% in trial group and 73.1% in control group on 3-7 d after menorrhea (P>0.05). There was no significant difference in clinical efficacy between two groups (P>0.05). No severe adverse reactions were found in the trial. The adverse reactions incidence in trial group was lower than that in control group(P<0.5). CONCLUSION Nifuratel-nysfungin suppository is an effective and safe preparation in the treatment of bacterial vaginosis. |
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| Keywords: | vaginosis bacterial nifuratel-nysfungin suppository metronidazole suppository |
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