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Levobunolol compared with timolol: a four-year study.
Authors:O Geyer   M Lazar   G D Novack   D Shen     C Y Eto
Affiliation:Department of Ophthalmology, Ichilove Medical Center, Sackler School of Medicine, University of Tel Aviv, Israel.
Abstract:Fifty-one patients with raised intraocular pressure (IOP) were treated for up to four years with one of three ophthalmic solutions: 0.5% levobunolol, 1% levobunolol, or 0.5% timolol. The study was conducted as a double-masked, randomised trial in which medications were administered twice daily to both eyes. Levobunolol and timolol were equally effective in reducing overall mean IOP; reductions were greater than 8.8 mmHg in all three treatment groups. The study showed levobunolol to be as safe and effective as timolol in the long-term control of raised IOP.
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