Spontaneous mutation results in loss of the cytadhesin (P1) of Mycoplasma pneumoniae. |
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| Authors: | C J Su A Chavoya J B Baseman |
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| Affiliation: | Department of Microbiology, University of Texas Health Science Center, San Antonio 78284-7758. |
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| Abstract: | The cytadhesin (P1) structural gene of a spontaneous mutant of Mycoplasma pneumoniae which displayed a P1-negative phenotype was analyzed. An extra adenine was discovered in a stretch of normally seven adenines near the N-terminal region of the mutant P1 structural gene. The frameshift mutation resulted in the early termination of protein translation. Possible causes of the mutation are discussed. |
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