Organ-Dependent Variation of Capsule Thickness in Cryptococcus neoformans during Experimental Murine Infection |
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| Authors: | Johanna Rivera Marta Feldmesser Michael Cammer Arturo Casadevall |
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| Affiliation: | Department of Microbiology and Immunology,1. Department of Medicine (Division of Infectious Diseases),2. and Department of Anatomy and Structural Biology,3. Albert Einstein College of Medicine, Bronx, New York 10461 |
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| Abstract: | In studies of murine infection, the capsule thickness of Cryptococcus neoformans varied depending on the organ. The relative order of thickness was as follows: lung > brain > in vitro isolates. The differences in capsule thickness suggest that there are organ-related differences in the expression of genes responsible for capsule thickness. |
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