| 细针穿刺细胞病理学在淋巴瘤诊断中的应用 |
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| 引用本文： | 周冬梅,陈刚,何诚,郑雄伟,力超. 细针穿刺细胞病理学在淋巴瘤诊断中的应用[J]. 白血病．淋巴瘤, 2013, 22(11): 674-677 |
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| 作者姓名： | 周冬梅 陈刚 何诚 郑雄伟 力超 |
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| 作者单位： | 福建省肿瘤医院病理科福建省肿瘤医学转化重点实验室, 福州,350014 |
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| 基金项目： | 福建省自然科学基金（2012J01326）;福建省创新基金（2012-CX-7） |
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| 摘 要： | 目的 探讨细针穿刺细胞学（FNC）检测在淋巴瘤诊断方面应用的可行性.方法 选择临床怀疑淋巴瘤的患者72例,行FNC检测并切取活组织行组织学病理诊断,对细胞学形态和免疫细胞化学进行分析.结果 72例中61例经FNC诊断为淋巴瘤,其中58例经组织病理学诊断.细胞学诊断敏感度为89.2％（58/65）,特异度为57.1％（4/7）,准确率为86.1％（62/72）,阳性预测值为95.1％（58/61）,阴性预测值为36.4％（4/11）.结论 FNC病理检查对淋巴瘤诊断是有应用价值且易被临床接受的方法,结合流式细胞术、免疫组织化学、荧光原位杂交等技术可提高淋巴瘤诊断的精确性,使淋巴瘤分型成为可能.
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| 关 键 词： | 淋巴瘤 细针穿刺 细胞学技术 诊断 |
Application of needle aspiration cytopathology in the lymphoma diagnosis |
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| ZHOU Oong-mei,CHEN Gang,HE Cheng,ZHENG Xiong-wei,LI Chao. Application of needle aspiration cytopathology in the lymphoma diagnosis[J]. Journal of Leukemia & Lymphoma, 2013, 22(11): 674-677 |
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| Authors: | ZHOU Oong-mei CHEN Gang HE Cheng ZHENG Xiong-wei LI Chao |
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| Affiliation: | . Department of Pathology, Fujicm Tumor Hospital, Key Laboratory of Carcinogenesis and Translational Research of Fujian Province, Fuzhou 350014, China |
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| Abstract: | Objective To investigate the feasibility of fine needle aspiration cytopathology in the diagosis of lymphoma.Methods To compare cytopathology with histopathology of 72 lymphoma cases and analyse immunochemistry stain of 3 cases.Results 61 of 72 cases were diagnosised as lymphoma in cytopathology,while 58 of 61 cases were diagnosised as lymphoma in histopathology.The sensitivity,specificity,accuracy,positive predictive value and negative predictive value rates of cytopathology were 89.2 % （58/65）,57.1% （4/7）,86.1% （62/72）,95.1% （58/61）,and 36.4 % （4/11） respectively.Conclusion Fine needle aspiration cytopathology is significant to the diagnosis of lymphoma.It should greatly improve the accuracy of lymphoma diagnosis and make it possible to subclassify lymphoma,combined cytopathology with other auxilary detection. |
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| Keywords: | Lymphoma Fine needle aspiration Cytological techniques Diagnosis |
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