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Fine structural evidence for hormone secretion by the human thymus
Authors:J. M. Vetters and R. F. Macadam
Affiliation:.University of Glasgow, Glasgow;.Department of Pathology, Western Infirmary, Glasgow
Abstract:The epithelial cells of the Hassall's corpuscles in 11 human thymus glands (nine cases of myasthenia gravis and two glands from patients undergoing surgical correction of congenital heart disease) have been examined by electron microscopy. In every instance the epithelial cells have the cytoplasmic organelle complex necessary for `export'-type secretory activity and in addition contain large numbers of membrane-limited small spheroidal secretion granules.
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