The effect of amino acid restricted diets on the clearance of 125I-labelled polyvinyl pyrrolidone in mice. |
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| Authors: | H M Coovadia and J F Soothill |
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| Abstract: | Impaired overall phagocytic function, as measured by clearance of radio-labelled polyvinyl pyrrolidone from the blood (KPVP), has been demonstrated in mice whose dietary intake of the essential amino acids phenylalanine and tryptophan was reduced to less than a quarter of that in a standard diet which supported optimal growth. This was associated with loss in weight of body, liver, spleen and thymus and an increase in the phagocytic index, alphaPVP. |
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