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The molecular epidemiology of Huntington disease is related to intermediate allele frequency and haplotype in the general population
Authors:Chris Kay  Jennifer A. Collins  Galen E.B. Wright  Fiona Baine  Zosia Miedzybrodzka  Folefac Aminkeng  Alicia J. Semaka  Cassandra McDonald  Mark Davidson  Steven J. Madore  Erynn S. Gordon  Norman P. Gerry  Mario Cornejo‐Olivas  Ferdinando Squitieri  Sarah Tishkoff  Jacquie L. Greenberg  Amanda Krause  Michael R. Hayden
Affiliation:1. Centre for Molecular Medicine Therapeutics, University of British Columbia, Vancouver, BC, Canada;2. Division of Human Genetics, Department of Pathology, University of Cape Town, South Africa;3. Division of Human Genetics, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa;4. Medical Genetics Group, School of Medicine and Dentistry, University of Aberdeen, Aberdeen, UK;5. Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research (A*STAR), Singapore;6. Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada;7. Molecular Biology Group, Coriell Institute for Medical Research, Camden, New Jersey;8. Neurogenetics Research Center, Instituto Nacional de Ciencias Neurologicas, Lima, Peru;9. IRCCS Casa Sollievo della Sofferenza Hospital, Huntington and Rare Diseases Unit (CSS‐Mendel Rome), San Giovanni Rotondo, Italy;10. Department of Genetics, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania;11. Division of Human Genetics, National Health Laboratory Service and School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Abstract:
Keywords:genetic epidemiology  haplotypes  Huntington disease  molecular epidemiology  trinucleotide repeat disorders
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