|
|||||
|
|
Estrogen Receptors in Human Breast Cancer |
|
| Authors: | William L. McGuire |
| Abstract: | Specific quantitative techniques have been used to measure the cytoplasmic estradiol-binding protein (EBP) in human mammary carcinoma tissue specimens. Sucrose gradient centrifugation reveals EBP to sediment at 8S and 4S. Variable quantities of non-specific estradiol binding occurs in the 4S region of the sucrose gradient necessitating controls to insure specificity of the estradiol protein interaction. |
| Keywords: | |