Quantification of Human Cytomegalovirus DNA in Amniotic Fluid of Mothers of Congenitally Infected Fetuses |
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| Authors: | Maria Grazia Revello Maurizio Zavattoni Milena Furione Fausto Baldanti Giuseppe Gerna |
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| Affiliation: | Servizio di Virologia, IRCCS Policlinico San Matteo, 27100 Pavia, Italy. virology@ipv36.unipv.it |
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| Abstract: | A quantitative PCR assay was used to quantitate human cytomegalovirus DNA in amniotic fluid of mothers of 21 fetuses with congenital infection. Seven fetuses presented ultrasound abnormalities or were born with symptoms, whereas 14 fetuses were subclinically infected. Although the median DNA level was higher in symptomatic fetuses, the difference was not statistically significant (P = 0.09). |
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