| 镇静镇痛对重型颅脑损伤患者术后颅内压的影响分析 |
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| 引用本文： | 徐帆,沈丽娟,钟兴明. 镇静镇痛对重型颅脑损伤患者术后颅内压的影响分析[J]. 中华神经创伤外科电子杂志, 2018, 4(5): 276-278. DOI: 10.3877/cma.j.issn.2095-9141.2018.05.006 |
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| 作者姓名： | 徐帆 沈丽娟 钟兴明 |
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| 作者单位： | 1. 313000 湖州，湖州师范学院护理学院2. 313000 湖州市第一人民医院神经外科 |
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| 基金项目： | 湖州市科技计划公益性技术应用研究课题(2015C102085) |
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| 摘 要： | 目的探讨镇静镇痛对重型、特重型颅脑损伤（TBI）患者术后颅内压（ICP）的影响。 方法选取湖州市第一人民医院神经外科自2016年1月至2018年6月收治的重型TBI患者45例，根据GCS评分将患者分为重型TBI组（GCS评分6~8分，26例）与特重型TBI组（GCS评分3~5分,19例），观察2组镇静镇痛下及撤除镇静镇痛/唤醒下ICP值波动情况。 结果特重型TBI患者在镇静镇痛前后ICP差异无统计学意义（P>0.05），重型TBI患者撤除镇静镇痛/唤醒后，ICP前后变化差异有统计学意义（P<0.05）。 结论镇痛镇静与重型TBI开颅术后颅内压力波动有显著相关性，使用镇静镇痛可获得安全、平稳的ICP。
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| 关 键 词： | 重型颅脑损伤 特重型颅脑损伤 镇静镇痛 颅内压 |
| 收稿时间： | 2018-08-11 |
Effects of sedation and analgesia on postoperative intracranial pressure in patients with severe traumatic brain injury |
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| Fan Xu,Lijuan Shen,Xingming Zhong. Effects of sedation and analgesia on postoperative intracranial pressure in patients with severe traumatic brain injury[J]. Chinese Journal of Neurotraumatic Surgery, 2018, 4(5): 276-278. DOI: 10.3877/cma.j.issn.2095-9141.2018.05.006 |
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| Authors: | Fan Xu Lijuan Shen Xingming Zhong |
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| Affiliation: | 1. School of Nursing, HuZhou University, Huzhou 313000, China2. Department of Neurosurgery, Huzhou First People’s Hospital, Huzhou 313000, China |
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| Abstract: | ObjectiveTo investigate the effect of sedation and analgesia on intracranial pressure (ICP) in patients with severe and severest traumatic brain injury(TBI). MethodsForty-five patients with severe TBI admitted to Department of Neurosurgery of Huzhou First People’s Hospital from January 2016 to June 2018 were divided into severe TBI group (GCS scores 6-8, 26 cases) and severest TBI (GCS scores 3-5, 19 cases) according to GCS score. Observing ICP value fluctuations under sedative and analgesia or withdrawal of sedative and analgesia/awake. ResultsThere was no significant difference in ICP between patients with severest TBI before and after sedation and analgesia (P>0.05). There was a significant difference in ICP changes before and after sedation and analgesia in patients with severe TBI(P<0.05). ConclusionAnalgesia and sedation are significantly correlated with intracranial pressure fluctuations after craniotomy operation for severe TBI. In severe TBI group, safe and stable ICP can be obtained by controlling sedation and analgesia. |
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| Keywords: | Severe traumatic brain injury Severest traumatic brain injury Sedation and analgesia Intracranial pressure |
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