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The orientation of the adjuvant activities of Salmonella typhosa lipopolysac-charide and lentinan |
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| Authors: | D. W. Dresser and J. M. Phillips |
| Abstract: | By using T cell-deprived mice and appropriate controls it has been shown that the adjuvant activity of LPS on the immune response to different doses of SRBC, tends to be oriented more towards B cells than towards T cells. In contrast, lentinan seems to mediate its adjuvant activity largely through a stimulatory effect on helper T cells. |
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