| 肿瘤短链脂肪酸代谢PET显像剂研究进展 |
| |
| 引用本文： | 张占文,胡平,唐刚华. 肿瘤短链脂肪酸代谢PET显像剂研究进展[J]. 国际放射医学核医学杂志, 2017, 41(6): 430-436. DOI: 10.3760/cma.j.issn.1673-4114.2017.06.009 |
| |
| 作者姓名： | 张占文 胡平 唐刚华 |
| |
| 作者单位： | 1.510080 广州, 中山大学附属第一医院核医学科PET/CT中心 |
| |
| 基金项目： | 国家自然科学基金(81571704)National Natural Science Foundation of China |
| |
| 摘 要： | 18F-FDG PET显像在临床上发挥着越来越重要的作用,但其在某些肿瘤的应用中存在一定的弊端,易产生假阳性和假阴性。脂肪酸代谢PET显像在脂类代谢显像中占有非常重要的地位,在一定程度上可弥补糖代谢的不足,能提高对肿瘤诊断的灵敏度和准确率。笔者就目前应用于临床前和临床研究中的肿瘤短链脂肪酸代谢PET显像剂进行综述。
|
| 关 键 词： | 短链脂肪酸 诊断 分子探针 正电子发射断层显像术 |
| 收稿时间： | 2017-06-28 |
Progress on short-chain fatty acid tumor molecular probes for PET imaging |
| |
| Zhang Zhanwen,Hu Ping,Tang Ganghua. Progress on short-chain fatty acid tumor molecular probes for PET imaging[J]. International Journal of Radiation Medicine and Nuclear Medicine, 2017, 41(6): 430-436. DOI: 10.3760/cma.j.issn.1673-4114.2017.06.009 |
| |
| Authors: | Zhang Zhanwen Hu Ping Tang Ganghua |
| |
| Affiliation: | 1.PET/CT Center, Department of Nuclear Medicine, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China |
| |
| Abstract: | 18F-FDG PET plays an increasingly important role in clinical assessment. However, some false-positive and false-negative results for certain tumors have been achieved with 18F-FDG. Furthermore, fatty acid metabolic imaging is valuable in lipid-metabolism PET imaging. This technique compensates for the deficiency of 18F-FDG PET examination and improves the diagnostic sensitivity and accuracy of tumor detection. This review provides an overview of recent developments in the use of short-chain fatty acid radioactive probes in PET imaging. |
| |
| Keywords: | Short-chain fatty acid Diagnosis Molecular probes Positron-emission tomography |
| 本文献已被 万方数据 等数据库收录！ |
| 点击此处可从《国际放射医学核医学杂志》浏览原始摘要信息 |
|
点击此处可从《国际放射医学核医学杂志》下载免费的PDF全文 |
