|
|||||
|
|
Role of interferon regulatory factor 1 in governing Treg depletion,Th1 polarization,inflammasome activation and antitumor efficacy of cyclophosphamide |
|
| Authors: | Federica Polverino Giovanna Ziccheddu Eleonora Aricò Filippo Belardelli Enrico Proietti Angela Battistini Federica Moschella |
| Affiliation: | 1. Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy;2. Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy |
| Abstract: | |
| Keywords: | cyclophosphamide regulatory T cell depletion IRF‐1 immune responses to anticancer drugs alkylating agents immunomodulation cytokines sterile inflammation |