A comparison of serum and saliva paracetamol concentrations. |
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| Authors: | M Smith E Whitehead G O''Sullivan F Reynolds |
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| Affiliation: | Anaesthetic Unit, St Thomas' Hospital, London. |
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| Abstract: | The relationship between serum and saliva paracetamol concentrations was investigated in twenty healthy volunteers. The plasma and saliva drug concentrations showed a significant correlation (r = 0.67). However the agreement between the two methods of measurement was poor with limits of agreement of -15.3 mg l-1 to +15.9 mg l-1 with mean sample values of 19.2 and 19.5 mg l-1 for plasma and saliva, respectively. |
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