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Intratumoral heterogeneity: Role of differentiation in a potentially lethal phenotype of testicular cancer
Authors:Shi‐Ming Tu MD  Mehmet Asim Bilen MD  Kenneth R. Hess PhD  Russell R. Broaddus MD  Scott Kopetz MD  PhD  Chongjuan Wei PhD  Lance C. Pagliaro MD  Jose A. Karam MD  John F. Ward MD  Christopher G. Wood MD  Priya Rao MD  Zachary H. Tu  Rosale General APRN  Adrienne H. Chen PharmD  Yago L. Nieto MD  PhD  Sai‐ching J. Yeung MD  PhD  Sue‐Hwa Lin PhD  Christopher J. Logothetis MD  Louis L. Pisters MD
Affiliation:1. Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas;2. Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas;3. Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas;4. Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas;5. Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas;6. Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas;7. Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, Texas;8. Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas;9. Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, Texas;10. Department of Emergency Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas
Abstract:
Keywords:integrated therapy  intratumoral heterogeneity  lethal phenotype  precision medicine  testicular cancer  yolk sac tumor
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