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Genetic anticipation in BRCA1/BRCA2 families after controlling for ascertainment bias and cohort effect
Authors:Rodrigo Santa Cruz Guindalini MD  Andrew Song  James D. Fackenthal PhD  Olufunmilayo I. Olopade MD  FACP  Dezheng Huo MD  PhD
Affiliation:1. Department of Medicine, Center for Clinical Cancer Genetics and Global Health, The University of Chicago, Chicago, Illinois;2. Department of Radiology and Oncology, The State of Sao Paulo Cancer Institute, University of Sao Paulo Medical School, Sao Paulo, Brazil;3. Clínica de Oncologia (CLION), Clínica de Assistência à Mulher (CAM) Group, Salvador, Bahia, Brazil;4. Department of Public Health Sciences, The University of Chicago, Chicago, Illinois
Abstract:
Keywords:ascertainment bias  breast cancer genes 1 and 2 (BRCA1/BRCA2)  cohort effect  genetic anticipation  hereditary breast and ovarian cancer syndrome
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