| 唐山市7～14岁肥胖儿童非酒精性脂肪肝流行现状及危险因素初步分析 |
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| 引用本文： | 陈新春,寇永妹,刘晓璐,李丹,杨雪冰. 唐山市7～14岁肥胖儿童非酒精性脂肪肝流行现状及危险因素初步分析[J]. 中国儿童保健杂志, 2021, 29(6): 669-673. DOI: 10.11852/zgetbjzz2020-1489 |
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| 作者姓名： | 陈新春 寇永妹 刘晓璐 李丹 杨雪冰 |
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| 作者单位： | 1.河北省唐山市人民医院儿科,河北 唐山 063001;2.河北省唐山市人民医院体检中心超声科 |
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| 摘 要： | 目的 初步了解唐山市肥胖儿童非酒精性脂肪肝(NAFLD)流行特点及危险因素,为早期干预提供理论依据.方法 以2018-2019年唐山市学龄儿童体检筛查出的肥胖儿童为研究对象,依年龄分组描述NAFLD患病率,比较NAFLD组与非NAFLD组代谢综合征(MetS)、体重指数(BMI)、腰围(WC)、腰围身高比(WHtR)、...
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| 关 键 词： | 非酒精性脂肪肝 肥胖 儿童 危险因素 |
| 收稿时间： | 2020-08-02 |
| 修稿时间： | 2020-11-18 |
Prevalence and risk factors of nonalcoholic fatty liver disease among obesity children aged 7 to 14 years in Tangshan city |
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| CHEN Xin-chun,KOU Yong-mei,LIU Xiao-lu,Li Dan,YANG Xue-bing. Prevalence and risk factors of nonalcoholic fatty liver disease among obesity children aged 7 to 14 years in Tangshan city[J]. Chinese Journal of Child Health Care, 2021, 29(6): 669-673. DOI: 10.11852/zgetbjzz2020-1489 |
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| Authors: | CHEN Xin-chun KOU Yong-mei LIU Xiao-lu Li Dan YANG Xue-bing |
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| Affiliation: | Department of Pediatrics,Tangshan municipal people's Hospital,Tangshan,Hebei 063001,China |
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| Abstract: | Objective To investigate the epidemiological characteristics and risk factors of nonalcoholic fatty liver disease (NAFLD) in obesity children in Tangshan,in order to provide reference for the early intervention. Methods Obesity children screened by physical examination of school-age children in Tangshan City from 2018 to 2019 were the study objects. The prevalence of NAFLD was described by age,and indicators were compared between NAFLD group and non-NAFLD group to analyze the risk factors of NAFLD,including metabolic syndrome (MetS),body mass index (BMI),waist circumference(WC),waist-to-height ration(WHtR),transaminase,uric acid(UA),glucose and lipid metabolism index. Results 1) The prevalence of NAFLD in obesity children in Tangshan was 34.62%,and there was no significant difference between boys and girls (χ2=0.009,P=1.000). The prevalence of NAFLD increased with age (r=0.425,P＜0.001). 2) The prevalence rate of lipid metabolism disorder in 7- to 9-year-old children and 10- to 14-year-old children,and the prevalence rate of hypertension,MetS in 10- to 14-year-old children in NAFLD group were significantly higher than those in non-NAFLD group(χ2=6.159,10.994,5.543,4.524,P＜0.05). 3) Multivariate Logistic regression analysis showed that the risk factors of NAFLD included older age,hyperuricemia(HUA),higher BMI,higher ALT(OR=3.91,2.09,1.07,1.04,P<0.05). Conclusions The overall prevalence rate of obese children in Tangshan is at a high level,and the prevalence rate of NAFLD increases with age. The onset of NAFLD in obese children is closely related to older age,HUA,higher BMI and ALT level. |
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| Keywords: | nonalcoholic fatty liver obesity children risk factor |
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