| 不孕女性维生素D水平与卵巢储备功能的相关性研究 |
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| 引用本文： | 徐上,栗嘉明,马娟. 不孕女性维生素D水平与卵巢储备功能的相关性研究[J]. 蚌埠医学院学报, 2022, 47(9): 1192-1195. DOI: 10.13898/j.cnki.issn.1000-2200.2022.09.009 |
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| 作者姓名： | 徐上 栗嘉明 马娟 |
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| 作者单位： | 安徽医科大学附属宿州医院 生殖医学中心，安徽 宿州 234000 |
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| 基金项目： | 安徽医科大学校科研基金项目2020xkj261 |
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| 摘 要： | 目的探讨不孕女性维生素D水平与卵巢储备功能各指标之间的相关性。方法选取不孕女性80例，检测25(OH)D3、抗苗勒氏管激素(AMH)、促卵泡激素(FSH)水平，超声检查观察窦卵泡计数(AFC)，分析25(OH)D3水平与AMH、FSH、AFC各指标的相关性。结果80例不孕女性中，维生素D缺乏26例(32.50%)，不足19例(23.75%)，充足35例(43.75%)。按照维生素D缺乏、不足和充足分组，3组年龄、体质量指数、不孕年限、不孕原因和AMH、AFC、FSH各指标差异均无统计学意义(P>0.05)。多重线性回归显示，25(OH)D3水平与AMH、FSH、AFC指标均无明显相关关系(P>0.05)。结论不孕女性维生素D水平与卵巢储备功能各项指标均无明显相关关系，补充维生素D可能没有改善不孕女性卵巢储备功能的作用。
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| 关 键 词： | 不孕 维生素D 卵巢储备功能 |
| 收稿时间： | 2022-02-28 |
Correlation between vitamin D level and ovarian reserve function in infertile women |
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| Affiliation: | Reproductive Medicine Centre, Suzhou Hospital of Anhui Medical University, Suzhou Anhui 234000, China |
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| Abstract: | ObjectiveTo investigate the correlation between vitamin D level and ovarian reserve function in infertile women.MethodsEighty infertile women were selected.25(OH)D3, anti-Müllerian hormone (AMH), follicular stimulating hormone (FSH) level were detected.Sinus follicle count (AFC) was observed by ultrasonography.The correlation between 25(OH)D3 level and AMH, FSH, AFC was analyzed.ResultsAmong the 80 infertile women, 26 cases(32.50%) were deficient in vitamin D, 19 cases(23.75%) were insufficient in vitamin D, and 35 cases(43.75%) were sufficient in vitamin D.There were no significant differences in age, body mass index, infertility years, infertility reasons and endocrine among the 3 groups of patients with different 25(OH)D3 level (P>0.05).Multiple linear regression showed that 25(OH)D3 level was not correlated with AMH, FSH, AFC(P>0.05).ConclusionsThere was no correlation between vitamin D level and various indicators of ovarian reserve function in infertile women, and vitamin D supplementation may not improve ovarian reserve function in infertile women. |
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