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Major histocompatibility complex class II antigen expression in B and T cell non-Hodgkin''s lymphoma. |
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| Authors: | M E Smith C S Holgate J M Williamson I Grigor P Quirke C C Bird |
| Abstract: | An immunohistochemical study of 46 B and T cell non-Hodgkin's lymphomas, using monoclonal antibodies to the products of the major histocompatibility complex (MHC) class II antigen subregions, DP, DQ, and DR, showed that most B and T cell lymphomas express these antigens. Both coordinate and non-coordinate expression of MHC class II antigens was observed, but this did not correlate with immunological phenotype, morphological grade, or proliferation index as determined by flow cytometry. |
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