| 正交设计优选益气祛白颗粒提取工艺 |
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| 引用本文： | 吴佳琪,周芳军,刘皋林,张彤,陶建生. 正交设计优选益气祛白颗粒提取工艺[J]. 中国药师, 2010, 13(4): 489-491 |
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| 作者姓名： | 吴佳琪 周芳军 刘皋林 张彤 陶建生 |
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| 作者单位： | 1. 上海交通大学附属第一人民医院药剂科,上海,200080
2. 上海中医药大学中药学院 |
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| 基金项目： | 上海市科委中药现代化专项基金资助项目，上海交通大学医学院科技基金项目，2008院通讯课题基金项目 |
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| 摘 要： | 目的：研究益气祛白颗粒的最佳水提工艺。方法：选用L9（34）进行正交设计试验，以黄芪甲苷含量和浸膏得率为评价指标，设定煎煮次数、煎煮时间、加水倍数为影响因素，优选益气祛白颗粒的最佳提取工艺。结果：得到最佳工艺条件为加10倍量的水，提取3次，每次1h。结论：优选出益气祛白颗粒水提工艺，该工艺稳定可行，有效成分提取效率高。
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| 关 键 词： | 正交设计 黄芪甲苷 提取工艺 |
Optimization of Extraction Conditions of Yiqi Qubai Granules by Orthogonal Design |
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| Wu Jiaqi,Zhou Fangjun,Liu Gaolin,Zhang Tong,Tao Jiansheg. Optimization of Extraction Conditions of Yiqi Qubai Granules by Orthogonal Design[J]. China Pharmacist, 2010, 13(4): 489-491 |
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| Authors: | Wu Jiaqi Zhou Fangjun Liu Gaolin Zhang Tong Tao Jiansheg |
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| Affiliation: | (College of Chinese Pharmacy, Shanghai University of TCM) |
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| Abstract: | Objective： To study the optimizing water extraction conditions of yiqi qubai granules. Method： The extracting condi- tions were optimized by using L9 （34 ） orthogonal test. The content of astragaloside IV and extract yield were used as indexes, the effects of the decoction frequeney, the time of extracting, the amount of water on the extracting process were investigated. Result： The most fa- vorable condition was performed by 1 hour extraction for three times, with 10 times amount of water. Conclusion： Optimum conditions of water＇ extraction of yiqi qubai granules are obtained and the optimized extraction technology is stable and efficient. The extraction rate of the effective principles is high. |
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| Keywords: | Orthogonal design Astragaloside IV Extracting process |
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