| 88例淋病患者耐药性分析 |
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| 引用本文： | 李海英,曾成龙,王胜春,冯婷,朱参胜,毛伟华. 88例淋病患者耐药性分析[J]. 中国麻风皮肤病杂志, 2019, 35(7): 406-408. DOI: 10.12144/zgmfskin201907406 |
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| 作者姓名： | 李海英 曾成龙 王胜春 冯婷 朱参胜 毛伟华 |
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| 作者单位： | 1第四军医大学西京皮肤医院，陕西西安，7100322陕西省皮肤性病防治所，陕西西安，710003 |
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| 摘 要： | 目的：检测淋病患者的耐药性。方法：收集2016年9月至2018年12月我院性病门诊淋病患者，利用E-test法测定青霉素、四环素、环丙沙星、大观霉素、头孢曲松、头孢克肟和阿奇霉素七种抗生素的最小抑菌浓度(MIC)。结果：共收集淋病患者88例，男77例，女11例。环丙沙星耐药86例（97.73%），青霉素耐药63例（71.59%），四环素耐药54例（61.36%），阿奇霉素耐药17例（19.32%），头孢克肟耐药1例（1.14%），大观霉素和头孢曲松无耐药。结论：头孢曲松、头孢克肟和大观霉素仍为治疗淋病的首选药物。
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| 关 键 词： | 淋病 临床特点 耐药性 |
Drug resistance test in 88 patients with gonorrhea |
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| LI Haiying,ZENG Chenglong,WANG Shengchun,FENG Ting,ZHU Cansheng,MAO Weihua. Drug resistance test in 88 patients with gonorrhea[J]. China Journal of Leprosy and Skin Diseases, 2019, 35(7): 406-408. DOI: 10.12144/zgmfskin201907406 |
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| Authors: | LI Haiying ZENG Chenglong WANG Shengchun FENG Ting ZHU Cansheng MAO Weihua |
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| Affiliation: | 1. Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi‘an 710032, China; 2. The Prevention and Control of Dermatology and Sexually Transmitted Diseases at Shaanxi Province, Xi’an 710003, China |
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| Abstract: | Objective: To detect drug resistance of patients with gonorrhea. Methods: The patients with gonorrhoea were collected from September 2016 to December 2018. The minimum inhibitory concentrations (MICs) were determined by E-test for penicillin, tetracycline, ciprofloxacin, meleumycin, ceftriaxone, cefixime and azithromycin. Results: Eighty eight patients were collected, including 77 males and 11 females. The drug sensitivities were 97.73% (86 cases) for ciprofloxacin, 71.59% (63) for penicillin, 61.36% (54) for tetracycline resistance, 19.32% (17) for azithromycin, 1.14% (1) for cefixime, respectively, (and no patient resistance to meleumycin and ceftriaxone. Conclusion: Meleumycin, cepixime and ceftriaxone are still the first choice in the treatment of gonorrhea. |
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| Keywords: | gonorrhea clinical characteristics drug resistance |
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