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Design and Synthesis of Substituted Pyridazinone‐1‐Acetylhydrazones as Novel Phosphodiesterase 4 Inhibitors
Authors:Hamdy M. Abdel‐Rahman  Mohamed Abdel‐Aziz  Heather N. Tinsley  Bernard D. Gary  Joshua C. Canzoneri  Gary A. Piazza
Affiliation:1. Department of Medicinal Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt;2. Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia, Egypt;3. Department of Biology, Chemistry and Mathematics, University of Montevallo, Montevallo, AL, USA;4. Mitchell Cancer Institute, University of South Alabama, Mobile, AL, USA
Abstract:
Keywords:Docking  N‐Acylhydrazones  PDE4B inhibitors  Pyridazinones
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