| 星形胶质细胞的电离辐射损伤及修复作用 |
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| 引用本文： | 高荣莲,陈肖华. 星形胶质细胞的电离辐射损伤及修复作用[J]. 国际放射医学核医学杂志, 2004, 28(1): 37-40 |
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| 作者姓名： | 高荣莲 陈肖华 |
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| 作者单位： | 100850 北京, 军事医学科学院放射医学研究所 |
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| 摘 要： | 星形胶质细胞(astrocyte, Ast)是中枢神经系统内最多的胶质细胞。体内外实验结果表明,电离辐射作用于神经系统后,可引起神经元、胶质细胞和血管内皮细胞等多种细胞的形态和功能变化。照射后早期Ast即可发生反应,与脑组织损伤后的病理过程及损伤后修复有着密切的联系。研究Ast在辐射损伤中的作用对于临床放射性脑损伤的治疗有着重要的意义。
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| 关 键 词： | 星形胶质细胞 电离辐射 中枢神经系统 |
| 文章编号： | 1001-098X(2004)01-0037-04 |
| 收稿时间： | 2003-06-27 |
| 修稿时间： | 2003-06-27 |
Injury and repair of astrocyte after ionizing radiation |
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| GAO Rong-lian CHEN Xiao-hua. Injury and repair of astrocyte after ionizing radiation[J]. International Journal of Radiation Medicine and Nuclear Medicine, 2004, 28(1): 37-40 |
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| Authors: | GAO Rong-lian CHEN Xiao-hua |
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| Affiliation: | Institute of Radiation Medicine, Academy of Military Medical Science, Beijing 100850, China |
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| Abstract: | Astrocyte is the most glial cell in the central nervous system.In the present experi-ment,radiation injury to the central nervous system(CNS)triggers a large network of cellular changes including neuron,glialcell and endothelial cell in morphology and metabolism and function.Astrocyte changes rapidly after ionizing radiation.There is a ralationship between astrocyte and the pathologic process and function recover of damaged brain tissue following CNS injury.This suggests that astrocyte plays an important role in cure of clinical radiation injury. |
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| Keywords: | astrocyte ionizing radiation central nervous system |
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