Mycobacterium tuberculosis malate synthase- and MPT51-based serodiagnostic assay as an adjunct to rapid identification of pulmonary tuberculosis |
| |
| Authors: | Achkar Jacqueline M Dong Yuxin Holzman Robert S Belisle John Kourbeti Irene S Sherpa Tsering Condos Rany Rom William N Laal Suman |
| |
| Affiliation: | New York University School of Medicine, New York, New York 10016, USA. jachkar@aecom.yu.edu |
| |
| Abstract: | The 81-kDa malate synthase (MS; Rv 1837c) and the 27-kDa MPT51 (Rv 3803c) of Mycobacterium tuberculosis are immunodominant antigens recognized by serum antibodies from approximately 80% of human immunodeficiency virus-negative smear-positive tuberculosis patients from India. We now provide evidence that the use of the MS/MPT51-based serodiagnostic assay can serve as an adjunct to sputum microscopy in the rapid diagnosis of pulmonary tuberculosis. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
