Method for testing for human papillomavirus infection in patients with cervical intraepithelial disease |
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| Authors: | Lin Hsing-Pei Huang Yang-Yang Wu Hsueh-Yin Kao Jau-Tsuen |
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| Affiliation: | Department of Laboratory Medicine, Cathay General Hospital, Taipei, Taiwan, Republic of China. |
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| Abstract: | To determine whether DNA detection of high-risk human papillomavirus could represent a reliable screening technique and a useful follow-up method, we investigated the performance of the Hybrid Capture II assay in detecting high-grade cervical lesions. The test positivity at 1.86 pg/ml had a high sensitivity (94.7%) and improved specificity. It was also a suitable follow-up method for detecting the recurrence of cervical intraepithelial disease in patients. |
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