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Bio-oss骨代材料与Bio-gide膜治疗重度牙周病疗效评估
引用本文:束为,倪杰,徐艳,陈武. Bio-oss骨代材料与Bio-gide膜治疗重度牙周病疗效评估[J]. 口腔医学, 2010, 30(12): 744-746
作者姓名:束为  倪杰  徐艳  陈武
作者单位:南京医科大学口腔医学研究所,南京医科大学附属口腔医院牙周科,南京210029
摘    要:目的 观察联合应用Bio-oss骨代材料和Bio-gide胶原膜行引导骨组织再生术治疗重度牙周炎的疗效。方法 将46例重度牙周病患者随机分为实验组和对照组,各23例,实验组39颗患牙行Bio-oss、Bio-gide引导性组织再生术,对照组32颗患牙行常规翻瓣术刮治。分别记录术前,术后12个月患牙周牙探诊深度(periodontal probing depth,PPD)、附着丧失(attachment loss,AL)、龈沟出血指数(sulcus bleeding index,SBI)、牙松动度(teeth mobility,TM)及牙槽骨高度(alveolar bone height,AH)。结果 与术前相比两组术后PPD、AL、SBI、TM均明显减少,且有显著性差异,实验组疗效优于对照组。X线根尖片显示,实验组骨缺损区有新骨形成,AH增加;对照组未见新骨形成,AH无明显改善。而且实验组骨密度增强较对照组明显增多(P<0.05)。结论 牙周翻瓣术后植入Bio-oss骨代材料,联合应用Bio-gide可吸收胶原膜治疗重度牙周病能明显改善临床指标,且疗效优于单纯翻瓣刮治术。

关 键 词:引导组织再生术   Bio-oss骨代材料   Bio-gide胶原膜   牙周翻瓣术   重度牙周病  

Clinic evaluation of Bio-oss artificial bone and Bio-gide collagen membrane on treating serious periodontal disease
SHU Wei,NI Jie,XU Yan,CHEN Wu. Clinic evaluation of Bio-oss artificial bone and Bio-gide collagen membrane on treating serious periodontal disease[J]. Stomatology, 2010, 30(12): 744-746
Authors:SHU Wei  NI Jie  XU Yan  CHEN Wu
Affiliation:.(Institute of Stomatology,Department of Periodontal,the Stomatological Hospital Affiliated to Nanjing Medical University, Nanjing 210029,China)
Abstract:Objective To observe the effect of biocompatibility of Bio-oss artificial bone and Bio-gide collagen membrane on treatment of serious periodontal disease. Methods 46 patients with serious periodontal disease were divided into two groups. One was treated by Bio-oss artificial bone and Bio-gide collagen membrane with guided tissue regeneration,GTR,while the other group was treated by routine flap surgery. Periodontal probing depth (PPD),attachment loss (AL),sulcus bleeding index (SBI),teeth mobility (TM) and alveolar bone height(AH) were scored before surgery respectively. After surgery,the above indices were examined again in the 12 th month. Results Compared with preparactive cases,the following indices such as PPD,AL,SBI,TM were significantly reduced in both groups(P 0.05). But the Bio-oss artificial bone and Bio-gide collagen membrane with GTR group had better effect than the contrast group. Conclusions Clinical effects of treating severe periodontal disease by flap curettage plus biocompatibility of Bio-oss artificial bone and Bio-gide collagen membrane are superior than by only periodontal flap curettage according to our clinical study.
Keywords:guided tissue regeneration  Bio-oss artificial bone  Bio-gide collagen membrane  periodontal flap surgery  serious periodontal disease
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