Shift of excretory-secretory immunogens of Trypanosoma cruzi during human Chagas'' disease. |
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Authors: | E E Jazí n, A O Luquetti, A Rassi, A C Frasch |
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Affiliation: | Instituto de Investigaciones Bioquímicas, Luis F. Leloir, Fundación Campomar, Buenos Aires, Argentina. |
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Abstract: | We studied secreted-excreted immunogens in human patients infected with Trypanosoma cruzi. A pair of 45- to 55-kDa antigens and a family of shed acute-phase antigens characterized the acute phase, while antibodies against a 160- to 170-kDa immunogen appeared at the chronic phase of the disease. |
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