Alterations in outer membrane proteins of Pseudomonas aeruginosa associated with selective resistance to quinolones. |
| |
| Authors: | G L Daikos V T Lolans G G Jackson |
| |
| Affiliation: | Department of Medicine, University of Illinois College of Medicine, Chicago 60680. |
| |
| Abstract: | Electrophoresis of outer membrane proteins in three ciprofloxacin-resistant strains of Pseudomonas aeruginosa isolated during therapy and their in vitro revertants indicated that diminution or loss of a 31- to 32-kilodalton outer membrane protein correlated with resistance in two of the three isolates. Resistance was unstable and caused no cross-resistance with other antibiotics. |
| |
| Keywords: | |
|
