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Pb2+ induces gastrin gene expression by extracellular signal‐regulated kinases 1/2 and transcription factor activator protein 1 in human gastric carcinoma cells
Authors:Chien‐Pin Chan  Yao‐Ting Tsai  Yao‐Li Chen  Yu‐Wen Hsu  Joseph T. Tseng  Hung‐Yi Chuang  Robert Shiurba  Mei‐Hsien Lee  Jaw‐Yuan Wang  Wei‐Chiao Chang
Affiliation:1. Transplant Medicine and Surgery Research Centre, Department of General Surgery, Changhua Christian Hospital, Changhua, Taiwan;2. Department of Clinical Pharmacy, School of Pharmacy, Taipei Medical University, Taipei, Taiwan;3. Institute of Master Program for Clinical Pharmacogenomics and Pharmacoproteomics, School of Pharmacy, Taipei Medical University, Taipei, Taiwan;4. Transplant Medicine and Surgery Research Centre, Changhua Christian Hospital, Changhua, Taiwan;5. School of Medicine, Chung Shan Medical University, Taichung, Taiwan;6. Institute of Bioinformatics and Biosignal Transduction, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, Taiwan;7. Department of Public Health, College of Health Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan;8. Integrative Bioscience and Biomedical Engineering, Graduate School of Science and Engineering, Waseda University, Japan;9. Graduate Institute of Pharmacognosy, College of Pharmacy, Taipei Medical University, Taipei, Taiwan;10. Cancer Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan;11. Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan;12. Division of Gastroenterologic and General Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan;13. Department of Pharmacy, Taipei Medical University‐Wanfang Hospital, Taipei, Taiwan
Abstract:
Keywords:c‐Jun  gastrin  ERK  lead (Pb2+)
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