| 2016-2018年新生儿重症监护室内轮状病毒感染流行病学特点分析 |
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| 引用本文： | 袁娇,汪际英,朱冬庆. 2016-2018年新生儿重症监护室内轮状病毒感染流行病学特点分析[J]. 现代预防医学, 2019, 0(21): 3902-3905 |
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| 作者姓名： | 袁娇 汪际英 朱冬庆 |
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| 作者单位： | 银川市妇幼保健院,宁夏 银川 750001 |
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| 摘 要： | 目的 研究新生儿重症监护室(neonatal intensive care unit,NICU)内轮状病毒(rotavirus,RV)感染流行病学特点,为临床疾病治疗及预防提供指导。方法 收集2016-2018年入住NICU病人7082例粪便标本,使用ELISA法检测大便RV抗原,分为阳性感染者及正常者,应用SPSS 19.0对影响其感染RV的因素进行分析。结果 7082例新生儿患者中检出RV感染419例,检出率5.91％,其中2016年检出率为3.90%(91/2330);2017年检出率6.36%(152/2391);2018年检出率7.45%(176/2361)。男性患儿RV阳性率为6.6%,女性为5.2%,二者RV感染率无统计学意义(P>0.05);2016-2018年晚期新生儿的轮状病毒感染率高于早期新生儿(χ2＝39.19,P<0.05;χ2＝50.72,P<0.001;χ2＝47.71,P<0.001)。2016-2018年的春、夏、秋、冬四季轮状病毒检出率分别为4.0％(70/1734),6.0％(99/1647),8.3％(150/1815),5.3％(100/1886)。不同民族(χ2＝16.94,P<0.01)、出生时体重(χ2＝76.47,P<0.01)的新生儿RV阳性率不同。结论 新生儿RV感染是多种不同因素共同作用的结果,要制定综合防治措施,从源头上抑制RV感染的暴发和流行,在流行季节要注意隔离患儿,以减少院内感染的发生。
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| 关 键 词： | 新生儿 重症监护室 轮状病毒 流行病学 |
Epidemiological characteristics and related factors of rotavirus infection in neonatal intensive care unit,2016-2018 |
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| YUAN Jiao,WANG Ji-ying,ZHU Dong-qing. Epidemiological characteristics and related factors of rotavirus infection in neonatal intensive care unit,2016-2018[J]. Modern Preventive Medicine, 2019, 0(21): 3902-3905 |
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| Authors: | YUAN Jiao WANG Ji-ying ZHU Dong-qing |
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| Affiliation: | Department of Neonatology,Yinchuan Women and Children Health care Hospital,Yinchuan,Ningxia 750000,China |
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| Abstract: | Objective To study the epidemiological characteristics of rotavirus(RV)infection in a neonatal intensive care unit(NICU),and to provide guidance for clinical disease treatment and prevention.Methods The stool samples of 7082 patients admitted to NICU in 2016-2018 were collected.The RV antigen was detected by ELISA.The patients were divided into the positively infected and the normal.SPSS19.0 software was used to analyze the factors affecting RV infection.Results A total of 419 cases of RV infection were detected in 7082 neonates,the detection rate was 5.91%,of which the detection rate in 2016 was 3.90%(91/2330),6.36%(152/2391)in 2017 and 7.45%(176/2361)in 2018.The detection rates of RV in male children were 4.3%,7.1%,and 8.4% in 2016-2018,and the detection rates of RV in female children were 3.2%,5.7%,and 6.3%,respectively,both RV infection rate was not statistically significant(P>0.05).The rate of rotavirus infection in neonates in late was higher than that in early neonates from 2016-2018(χ2=39.19,P<0.05;χ2=50.72,P<0.001;χ2=47.71,P<0.001).The detection rates of rotavirus in spring,summer,autumn and winter in 2016-2018 were 4.0%(70/1734),6.0%(99/1647),8.3%(150/1815)and 5.3%(100/1886).The RV positive rates of neonates in different ethnic groups(χ2=16.94,P<0.01),birth weight(χ2=76.47,P<0.01)were different.Conclusion Neonatal RV infection is the result of a combination of different factors.Comprehensive prevention and treatment measures should be developed to suppress the outbreak and epidemic of RV infection from the source.In the epidemic season,children should be isolated to reduce the incidence of nosocomial infection. |
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| Keywords: | Neonatal Intensive care unit Rotavirus Epidemiology |
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