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| 简明围术期疲劳评测量表的汉化及其在消化道肿瘤术后患者中的应用价值研究 | |
| 引用本文： | 徐欣怡,许勤. 简明围术期疲劳评测量表的汉化及其在消化道肿瘤术后患者中的应用价值研究[J]. 中国全科医学, 2019, 22(2): 210-214. DOI: 10.12114/j.issn.1007-9572.2018.00.250 |
| 作者姓名： | 徐欣怡 许勤 |
| 作者单位： | 211166江苏省南京市，南京医科大学护理学院 *通信作者：许勤，副教授，硕士生导师；E-mail：248629512@qq.com |
| 基金项目： | 基金项目：江苏省研究生科研与实践创新计划项目（SJCX17_0393） |
| 摘 要： | 背景 术后疲劳（POF）在消化道肿瘤人群中具有较高的发生率且对患者预后和生活质量产生了严重影响。目前尚无针对消化道肿瘤术后患者POF的简便评估工具，且现有评估量表均具有一定的局限性。目的 汉化10条目简明围术期疲劳评测量表（ICFS-10），对其进行信效度检验，并确定其诊断消化道肿瘤术后患者POF的截断值。方法 采用方便抽样法选取2017年11月—2018年1月在江苏省人民医院行手术治疗的消化道肿瘤患者80例为调查对象。遵循美国矫形外科医师学会循证医学委员会推荐的跨文化调适指南，通过前译、回译、专家咨询，形成中文版ICFS-10。采用一般情况调查表、中文版ICFS-10、中文版Piper癌因性疲乏修订量表（PFS-R）、中文版医院焦虑抑郁量表（HADS）对调查对象进行调查。分析中文版ICFS-10信效度；通过受试者工作特征（ROC）曲线和阈值效应分析确定中文版ICFS-10诊断消化道肿瘤术后患者POF的截断值。结果 采用临界比值法将患者分为高分组（20例）和低分组（20例），高分组中文版ICFS-10各条目得分均高于低分组（P<0.05）。中文版ICFS-10各条目得分与其总分均呈正相关（P<0.05）。中文版ICFS-10各条目的内容效度指数（CVI）为0.86~1.00，中文版ICFS-10的CVI为0.96。中文版ICFS-10的KMO值为0.868，Bartlett's球形检验χ2=780.99，P<0.001，表明适合做探索性因子分析。在探索性因子分析中，按特征值≥1.000的标准可提取2个公因子，其特征值分别为6.191、1.543，累积方差贡献率为77.34%，各条目的载荷值为0.588~0.918。中文版ICFS-10总分与中文版PFS-R总分呈正相关（P<0.05）。中文版ICFS-10的Cronbach's α系数为0.928，提取的2个公因子的Cronbach's α系数分别为0.907和0.877。中文版ICFS-10诊断消化道肿瘤术后患者POF的ROC曲线下面积为0.833〔95%CI（0.729，0.910）〕，Youden指数最大值为0.595，此时灵敏度为80.6%，特异度为79.0%，对应的截断值为22分；阈值效应分析结果显示，折点K值为24〔95%CI（12，27）〕，对数似然比为0.074；结合两个截断值可得，中文版ICFS-10诊断消化道肿瘤术后患者POF的截断值为24分。以中文版ICFS-10总分>24分为POF明显且影响患者生理、心理水平对患者进行评估，结果显示，49例（66.2%）患者得分>24分。结论 中文版ICFS-10信效度良好，可有效评估POF。中文版ICFS-10诊断消化道肿瘤术后患者POF的截断值为24分，可作为POF对患者生理、心理均产生不利影响的警示值。 |
| 关 键 词： | 胃肠肿瘤 疲劳 信度 效度 手术后期间 |
Chinesization of the 10-item Identity-Consequence Fatigue Scale and Its Application in Patients after Gastrointestinal Tumor Surgery |
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| XU Xinyi,XU Qin. Chinesization of the 10-item Identity-Consequence Fatigue Scale and Its Application in Patients after Gastrointestinal Tumor Surgery[J]. Chinese General Practice, 2019, 22(2): 210-214. DOI: 10.12114/j.issn.1007-9572.2018.00.250 | |
| Authors: | XU Xinyi XU Qin |
| Affiliation: | School of Nursing，Nanjing Medical University，Nanjing 211166，China *Corresponding author：XU Qin，Associate professor，Master supervisor；E-mail：248629512@qq.com |
| Abstract: | Background Postoperative fatigue（POF）has a high incidence and a serious impact on prognosis and quality of life for patients after gastrointestinal tumor surgery.At present，there is no simple and targeted tool for gastrointestinal tumor patients to assess POF.In addition，the existing assessment scales have some limitations.Objective To translate the 10-item Identity-Consequence Fatigue Scale（ICFS-10）into Chinese and test its reliability and validity and determine the optimal cut-off point in patients after gastrointestinal tumor surgery.Methods We developed the Chinese version of ICFS-10 based on the translation，back translation，revision based upon expert consultations and cultural adaptation guideline recommended by American Academy of Orthopaedic Surgeons Evidence Based Medicine Committee.Then，using it and the Chinese version of PFS-R，and Chinese version of HADS，we conducted a survey among a convenience sample of 80 patients who underwent gastrointestinal tumor surgery in Jiangsu Province Hospital from November 2017 to January 2018.The reliability and validity of the Chinese version of ICFS-10 were analyzed，and its optimal cut-off point was defined by ROC analysis and threshold effect analysis.Results According to the scale score of the Chinese version of ICFS-10，these patients were divided into high-score group（n=20）and low-score group（n=20）by the critical ratio.High-score group scored higher in each item of the Chinese version of ICFS-10 compared with the low-score group（P<0.05）．Item score increased with the scale score of the Chinese version of ICFS-10（P<0.05）．The Chinese version of ICFS-10 demonstrated scale-level content validity index（CVI）of 0.96，item-level CVI of 0.86 to 1.00.KMO value of Chinese version of ICFS-10 was 0.868，Bartlett's test of χ2 was 780.99，P<0.001，indicating that it was suitable for exploratory factor analysis.Exploratory factor analysis indicated that Chinese version of ICFS-10 consisted of 2 factors with igenvalues of 6.191，1.543（extracted on the basis of the extraction decision rule of eigenvalue ≥1.000）which explained 77.34% of the total variance，and factor loading of all 10 items ranged 0.588 to 0.918.The scale score of the Chinese version of ICFS-10 showed a positive correlation with that of the Chinese version of PFS-R（P<0.05）．The values of Cronbach's α for the scale and two common factors of the Chinese version of ICFS-10 were 0.928，0.907，0.877，respectively.For the diagnosis of POF，the AUC of the Chinese version of ICFS-10 was 0.833〔95%CI（0.729，0.910）〕，yielding a maximal Youden index of 0.595 with a sensitivity of 80.6%，specificity of 79.0%，and a cut-off point of 22.Threshold effect analysis revealed a change point（K）of 24〔95%CI（12，27）〕with a logarithmic likelihood ratio of 0.074.Therefore，the optimal cut-off point of the Chinese version of ICFS-10 was determined as 24 for the diagnosis of POF，and the evaluation of the physiology and psychology of such patients by this scale showed，49 cases（66.2% of the total）scored more than 24.Conclusion The Chinese version of ICFS-10 has good reliability and validity and can be used to assess the POF.Its optimal cut-off point of 24 can be used as a warning sign of the adverse effects of POF on physiological and psychological health. |
| Keywords: | Gastrointestinal neoplasms Fatigue Reliability Validity Postoperative period |
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