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新疆某医院入院患者高尿酸血症与常见慢性疾病关系研究
引用本文:王婷婷1,2,古丽夏提·麦麦提图尔逊2,史浩楠2,苏银霞3,徐文杰2,姚华3. 新疆某医院入院患者高尿酸血症与常见慢性疾病关系研究[J]. 现代预防医学, 2019, 0(21): 3989-3992
作者姓名:王婷婷1  2  古丽夏提·麦麦提图尔逊2  史浩楠2  苏银霞3  徐文杰2  姚华3
作者单位:1.上海健康医学院护理与健康管理学院,上海 201318;2.新疆医科大学公共卫生学院,新疆 乌鲁木齐 830011;3.新疆医科大学第一附属医院代谢性疾病实验室,新疆 乌鲁木齐 830011
摘    要:目的 探讨新疆维吾尔族人群高尿酸血症与常见慢性疾病的关系,为尿酸相关疾病预防、控制提供科学依据。方法 调查员经统一培训后对709名维吾尔族高尿酸血症患者进行问卷调查,并进行病例资料查询,获得生化指标和诊断,采用χ2检验和方差分析进行比较。结果 (1)入选的高尿酸血症中代谢综合征、高血压、高血糖、血脂紊乱的现患病率为42.3%、39.2%、12.12%、65.6%;呼吸、消化、肿瘤、循环、泌尿系统疾病的患病率为12.8%、9.2%、7.1%、35.4%、6.5%。其中最高的3种疾病为血脂紊乱、代谢综合征和高血压。代谢综合征、高血压、血脂紊乱、饮酒、吸烟的性别构成比男性均高于女性,χ2值分别为3.886、5.081、20.935、41.852和122.015,且差异具有统计学意义(P均<0.05)。(2)随着尿酸水平的增高,男性比例、泌尿系统疾病、高血糖和血脂紊乱人群比率随之增高,χ2值分别为375.653、14.616、7.980和146.020(P均<0.05);(3)随着尿酸水平的升高,收缩压、舒张压、FBG、甘油三酯逐渐增高,而HDL逐渐降低,F值分别为3.055、3.287、5.031、2.722和9.091(P均<0.05)。结论 高尿酸血症患者中血脂紊乱、代谢综合征和高血压等代谢性疾病的患病率较高;随着尿酸水平的升高,男性、泌尿系统疾病比率和血压、血糖、血脂指标随之增高。

关 键 词:尿酸  代谢性疾病  维吾尔族  慢性疾病  高尿酸血症

Relationship between hyperuricemia and common chronic diseases in hospitals,Xinjiang
WANG Ting-ting,GULIXIATI·MAI-mai-ti-tu-er-xun,SHI Hao-nan,SU Yin-xia,XU Wen-jie,YAO Hua. Relationship between hyperuricemia and common chronic diseases in hospitals,Xinjiang[J]. Modern Preventive Medicine, 2019, 0(21): 3989-3992
Authors:WANG Ting-ting  GULIXIATI·MAI-mai-ti-tu-er-xun  SHI Hao-nan  SU Yin-xia  XU Wen-jie  YAO Hua
Affiliation:*School of Nursing & Health Management,Shanghai University of Medicine & Health Science,Shanghai,Shanghai 201318,China
Abstract:Objective To investigate the relationships between hyperuricemia and common chronic diseases in Xinjiang Uygur population,and to provide scientific evidence for prevention and control of uric acid-related diseases.Methods After a unified training,the investigators conducted a questionnaire survey of 709 Uygur patients with hyperuricemia,and conducted case data query to obtain biochemical indicators and diagnosis.The χ2 test and analysis of variance were compared.Results (1)The prevalence of metabolic syndrome,hypertension,hyperglycemia and dyslipidemia in hyperuricemia were 42.3%,39.2%,12.12% and 65.6%.The prevalence of respiratory,digestive,tumor,circulatory,urinary systemic diseases were 12.8%,9.2%,7.1%,35.4% and 6.5%.The three highest diseases were dyslipidemia,metabolic syndrome and hypertension.The gender compositions of metabolic syndrome,hypertension,dyslipidemia,alcohol consumption and smoking were higher than those of males.The χ2 values were 3.886,5.081,20.935,41.852 and 122.015,respectively(P<0.05).(2)With the increase of uric acid level,the ratio of male proportion,urinary system disease,hyperglycemia and dyslipidemia increased,and χ2 values were 375.653,14.616,7.980 and 146.02,respectively(P<0.05).With the increase of uric acid level,systolic blood pressure,diastolic blood pressure,FBG and triglyceride increased gradually,while HDL decreased gradually,and the F values were 3.055,3.287,5.031,2.722 and 9.091,respectively(P<0.05).Conclusion The prevalence of metabolic disorders such as dyslipidemia,metabolic syndrome and hypertension is higher in patients with hyperuricemia.With the increase of uric acid level,the ratios of male and urinary diseases,blood pressure,blood sugar and blood lipids increase.
Keywords:Uric acid  Metabolic disease  Uygur  Chronic diseases  Hyperuricemia
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