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Peroxisome proliferator‐activated receptor‐γ coactivator‐1α mediates neuroprotection against excitotoxic brain injury in transgenic mice: role of mitochondria and X‐linked inhibitor of apoptosis protein
Authors:Dan Duc Pham  Valentina Di Liberto  Ove Eriksson  Lauri Louhivuori  Céline Bruelle  Rabah Soliymani  Marc Baumann  Laura Korhonen  Maciej Lalowski  Dan Lindholm
Affiliation:1. Medicum, Department of Biochemistry and Developmental Biology, Medical Faculty, University of Helsinki, Helsinki, Finland;2. Minerva Medical Research Institute, Biomedicum‐2 Helsinki, Tukholmankatu 8, FIN‐00290 Helsinki, Finland;3. Department of Experimental Biomedicine and Clinical Neuroscience, Division of Human Physiology, University of Palermo, Corso Tukory 129, I‐90134 Palermo, Italy;4. Medicum, Department of Physiology, University of Helsinki, Helsinki, Finland;5. Clinicum, Division of Child Psychiatry, Helsinki University Central Hospital, Helsinki, Finland
Abstract:
Keywords:kainic acid  mitochondria  neuron survival  PGC‐1α    proteomics     XIAP   
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