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K+‐channel inhibition reduces portal perfusion pressure in fibrotic rats and fibrosis associated characteristics of hepatic stellate cells
Authors:Ulrike Erben  Joachim Hoyer  Ralf Köhler  Korinna Jöhrens  Eleonora Patsenker  Martin Ruehl  Daniel Seehofer  Felix Stickel  Rajan Somasundaram
Affiliation:1. Department of Gastroenterology, Infectiology and Rheumatology, Charité – University Medicine Berlin, Berlin, Germany;2. Department of Internal Medicine and Nephrology, University Hospital, Philipps‐University, Marburg, Germany;3. I+CS and ARAID, Aragon Institute of Health Sciences, Zaragoza, Spain;4. Department of Pathology, Charité ‐ University Medicine Berlin, Berlin, Germany;5. Department of Clinical Research ‐ Hepatology, University of Berne, Berne, Switzerland;6. Department of General, Visceral and Transplantation Surgery, Charité – University Medicine Berlin, Berlin, Germany
Abstract:
Keywords:   HSC     KCa3.1  liver fibrosis  TGF‐β  1  TRAM‐34
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