| 动脉自旋标记法与体素内不相干运动成像在胶质瘤术前应用 |
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| 引用本文： | 张玉琴,徐海东,董海波,王波,徐田勇. 动脉自旋标记法与体素内不相干运动成像在胶质瘤术前应用[J]. 中国临床医学影像杂志, 2014, 25(9): 609-611 |
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| 作者姓名： | 张玉琴 徐海东 董海波 王波 徐田勇 |
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| 作者单位： | 1. 宁波市医疗中心李惠利医院磁共振室,浙江宁波,315041
2. 通用电气(中国)医疗集团,上海,201203 |
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| 摘 要： | 目的：探讨三维动脉自旋标记法（3D-ASL）与体素内不相干运动（IVIM）在脑胶质瘤术前分级中的应用价值。方法：选择45例经病理证实的胶质瘤患者（高级别26例,低级别19例）,均行3D-ASL、IVIM-DWI检查,于脑血流量图测量肿瘤实性部分灌注最明显区及健侧CBF值;按双指数模型拟合求得各量化参数,取快ADC（fastADC）图并测量与3D-ASL相同层面肿瘤实性部分与健侧ADC值。结果：高低级别胶质瘤CBF值患侧/健侧比值分别为3.11±1.45、0.86±0.28,fastADC值比值分别为1.88±0.51、0.96±0.31,高低级别组间差异有统计学意义（P〈0.05）。结论：3D-ASL与IVIM技术均可在术前安全无创地提取胶质瘤灌注信息以判断其级别。
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| 关 键 词： | 脑肿瘤 神经胶质瘤 磁共振成像 |
| 收稿时间： | 2014-03-08 |
Application of arterial spin labeling and intra-voxel incoherent motion imaging in preoperative glioma |
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| ZHANG Yu-qin , XU Hai-dong , DONG Hai-bo , WANG Bo , XU Tian-yong. Application of arterial spin labeling and intra-voxel incoherent motion imaging in preoperative glioma[J]. Journal of China Clinic Medical Imaging, 2014, 25(9): 609-611 |
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| Authors: | ZHANG Yu-qin XU Hai-dong DONG Hai-bo WANG Bo XU Tian-yong |
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| Affiliation: | ZHANG Yu-qin, XU Hai-dong, DONG Hai-bo, WANG Bo, XU Tian-yong (1.Department of Radiology, Ningbo Medical Center Lihuili Hospital, Ningbo Zhejiang 315041, China; 2.General Electric(China) Medical Group, Shanghai 201203, China) |
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| Abstract: | Objective：To investigate the three-dimensional arterial spin labeling（ASL） and intra-voxel incoherent motion（IVIM） value in preoperative grading of cerebral glioma. Materials and Methods： Forty-five patients with glioma proved by pathology（26 cases of high grade glioma and 19 cases of low grade glioma） underwent 3D-ASL and IVIM-DWI examination.Cerebral blood flow（CBF） in the most obvious perfusion area of the solid part of tumor and also in the contralateral normal area were measured using cerebral blood flow map. By fitting double exponential model, got the fast ADC map. On 3D-ASL,the ADC value in the solid part of the tumor and also in the contralateral normal area of the same section were measured.Results： CBF ratios of the lesion and contralateral normal area in high and low grade gliomas were 3.11±1.45 and 0.86±0.28 respectively, the fast ADC value were 1.88±0.51 and 0.96±0.31 respectively. There was significant differences between the two groups（P0.05）. Conclusion： 3D-ASL and IVIM techniques are safe and noninvasive methods to extract information of perfusion in gliomas and thus can be used as methods for determining the grade of gliomas before operation. |
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| Keywords: | Brain neoplasms Glioma Magnetic resonance imaging |
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