| 自拟益气健脾化湿方治疗脾虚湿蕴型溃疡性结肠炎缓解期临床效果研究 |
| |
| 引用本文： | 张丽萍, 陈欣欣, 陈博, 尚智. 自拟益气健脾化湿方治疗脾虚湿蕴型溃疡性结肠炎缓解期临床效果研究[J]. 中国现代应用药学, 2021, 38(11): 1379-1382. DOI: 10.13748/j.cnki.issn1007-7693.2021.11.018 |
| |
| 作者姓名： | 张丽萍 陈欣欣 陈博 尚智 |
| |
| 作者单位： | 1.1. 珠海市中西医结合医院治未病科, 广东 珠海 519020 |
| |
| 摘 要： | 目的 探讨自拟益气健脾化湿方治疗脾虚湿蕴型溃疡性结肠炎缓解期的临床疗效.方法 将2017年12月-2019年12月在浙江省立同德医院进行治疗的120例脾虚湿蕴型溃疡性结肠炎缓解期患者纳入研究,按照就诊时间采用随机、双盲、平行对照的方法,通过简单随机分组分为观察组和对照组,每组60例.对照组应用美沙拉嗪肠溶片治疗,观察组...
|
| 关 键 词： | 益气健脾化湿方 脾虚湿蕴型 溃疡性结肠炎 临床疗效 |
| 收稿时间： | 2021-01-25 |
| 修稿时间： | 2021-02-22 |
Study on Clinical Effect of Self-designed Yiqi Jianpi Huashi Decoction in the Remission Stage of Ulcerative Colitis with Spleen Deficiency and Damp Deposition Type |
| |
| ZHANG Liping, CHEN Xinxin, CHEN Bo, SHANG Zhi. Study on Clinical Effect of Self-designed Yiqi Jianpi Huashi Decoction in the Remission Stage of Ulcerative Colitis with Spleen Deficiency and Damp Deposition Type[J]. Chinese Journal of Modern Applied Pharmacy, 2021, 38(11): 1379-1382. DOI: 10.13748/j.cnki.issn1007-7693.2021.11.018 |
| |
| Authors: | ZHANG Liping CHEN Xinxin CHEN Bo SHANG Zhi |
| |
| Affiliation: | 1.1. Department of Preventive Medicine, Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine, Zhuhai 519020, China |
| |
| Abstract: | OBJECTIVE To explore the clinical efficacy of self-formulated Yiqi Jianpi Huasi decoction in the remission stage of ulcerative colitis with spleen deficiency and dampness accumulation type. METHODS A total of 120 patients with ulcerative colitis with spleen deficiency and dampness accumulation type treated in Tongde Hospital of Zhejiang Province from December 2017 to December 2019 were included in the study, and randomly divided into observation group and control group with 60 cases in each group according to the time of visit. The control group was treated with mesalazine enteric-coated tablet, and the observation group was treated with self-designed Yiqi Jianpi Huashi decoction, the treatment period was 12 weeks. The TCM symptom score, quality of life(SF-36) and the total clinical treatment effect of patients in the two groups were observed before and after treatment, and the adverse reactions during treatment were summarized and analyzed. RESULTS After treatment, TCM syndrome score and SF-36 score in the observation group were significantly higher than those in the control group, the differences were statistically significant(P<0.05). The total effective rate in the observation group was 93.33%, and that in the control group was 73.33%, which was significantly higher in the observation group than that in the control group(P<0.05). No serious adverse reactions occurred during the treatment. CONCLUSION The self-designed Yiqi Jianpi Huashi decoction is effective in the remission stage of ulcerative colitis with spleen deficiency and dampness accumulation type, which can significantly improve the main symptoms such as diarrhea, abdominal distension, abdominal pain, pus and blood stool, and further improve the quality of life. Besides, no serious adverse drug reactions have been observed in the treatment process, and the clinical application prospect is broad. |
| |
| Keywords: | Yiqi Jianpi Huashi decoction spleen deficiency and dampness accumulation type ulcerative colitis clinical efficacy |
|
| 点击此处可从《中国现代应用药学》浏览原始摘要信息 |
|
点击此处可从《中国现代应用药学》下载全文 |
|
