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An investigation of presynaptic α-adrenoceptor subtypes in the pithed rat heart |
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| Authors: | James R. Docherty |
| Abstract: | 1 The presynaptic cardio-inhibitory and postsynaptic pressor responses to the α-adrenoceptor agonists xylazine and cirazoline, and the interaction with the antagonists yohimbine and prazosin, were examined in the pithed rat. 2 Evidence was found to suggest that, as well as the already established pre- and postsynaptic α2- and postsynaptic α1-receptors, presynaptic α1-receptors are present. |
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